T3376

DL-α-Tocopherol acetate

≥96% (HPLC)

• Synonym(s): Vitamin E acetate, all-rac-α-Tocopheryl acetate
• Empirical Formula (Hill Notation): C₃₁H₅₂O₃
• CAS Number: 7695-91-2
• Molecular Weight: 472.74
• Beilstein: 97512
• EC Number: 231-710-0
• MDL number: MFCD00072042
• UNSPSC Code: 12352205
• PubChem Substance ID: 24900133
• NACRES: NA.79

Properties

• biological source: synthetic (organic)
• Assay: ≥96% (HPLC)
• form: viscous liquid
• technique(s): HPLC: suitable
• color: colorless to dark yellow
• density: 0.96 g/mL at 20 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
• InChI: 1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
• InChI key: ZAKOWWREFLAJOT-CEFNRUSXSA-N

Description

General description

α-Tocopherol is a predominant form of vitamin E in human and animal tissues and also in leaf chloroplasts. It is the major form in supplements. DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.

Application

DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats. It has also been used as a standard in α-tocopherol analysis using plasma sample and mature fresh tobacco leaves.

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): No data available
• Flash Point(C): No data available
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves