This product can be sterile-filtered after reconstitution down to 100 ug/mL. To avoid protein loss due to membrane binding, a PTFE or other low binding membrane is recommended.
P2533
Poly-L-ornithine hydrochloride
suitable for ligand binding assays, Mol wt 15,000-30,000
Synonym(s):
L-Ornithine homopolymer hydrochloride
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About This Item
CAS Number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Pricing and availability is not currently available.
Product Name
Poly-L-ornithine hydrochloride, mol wt 15,000-30,000
form
powder or solid
Quality Segment
mol wt
15,000-30,000
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
Cl.NCCCC(N)C(O)=O
InChI key
GGTYBZJRPHEQDG-UHFFFAOYSA-N
Application
Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.
Biochem/physiol Actions
Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.
Analysis Note
Molecular weight based on viscosity.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
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This Item | |||
|---|---|---|---|
| form powder or solid | form powder | form powder or solid | form powder or solid |
| technique(s) ligand binding assay: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| color white to off-white | color white to light yellow | color white to off-white | color white to off-white |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| mol wt 15,000-30,000 | mol wt 15,000-30,000 | mol wt 3,000-15,000 | mol wt >30,000 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hi! Once reconstituted and diluted for cell coating, can it be filtered with a PES filter? Thanks!
1 answer-
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