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H9268

Sigma-Aldrich

Hexadimethrine bromide

≥94% (titration)

Synonym(s):

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

CAS Number:
28728-55-4
MDL number:
MFCD00133397
UNSPSC Code:
41106502
NACRES:
NA.26

Quality Level

200

Assay

≥94% (titration)

storage temp.

2-8°C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

InChI key

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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General description

Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.

Application

Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.

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Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Blood (2013)
UCHL1 Is a Putative Tumor Suppressor in Ovarian Cancer Cells and Contributes to Cisplatin Resistance.
Jin C et al.
Journal of Cancer, 4, 662-662 (2013)
Redei GP
Encyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)
An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo.
Fang C et al.
Cardiovascular Research, 99, 146-146 (2013)
Molecular pathways regulating pro-migratory effects of Hedgehog signaling.
Hochman E et al.
The Journal of Biological Chemistry, 281, 33860-33860 (2006)
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