H5002

17α-Hydroxypregnenolone

coritsol precursor

• Synonym(s): 3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
• Empirical Formula (Hill Notation): C₂₁H₃₂O₃
• CAS Number: 387-79-1
• Molecular Weight: 332.48
• NACRES: NA.77
• PubChem Substance ID: 24895665
• UNSPSC Code: 41116107
• EC Number: 206-862-6
• MDL number: MFCD00021129

Properties

• Product Name: 17α-Hydroxypregnenolone,
• Quality Segment: 100
• SMILES string: C[C@]1(CC[C@H](O)C2)C2=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(C(C)=O)O
• InChI: 1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3
• InChI key: JERGUCIJOXJXHF-UHFFFAOYSA-N

Description

General description

17α-hydroxypregnenolone is a derived from pregnenolone.

Application

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

Biochem/physiol Actions

17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)