C2522
Carbonic Anhydrase Isozyme II from bovine erythrocytes
lyophilized powder, ≥3,000 W-A units/mg protein
Synonym(s):
Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase II
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|
About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-576-6
MDL number:
Specific activity:
≥3,000 W-A units/mg protein
Biological source:
bovine erythrocytes
Pricing and availability is not currently available.
biological source
bovine erythrocytes
Quality Level
form
lyophilized powder
specific activity
≥3,000 W-A units/mg protein
mol wt
30 kDa
pI
~5.9
storage temp.
−20°C
Application
Carbonic anhydrase from sigma has been used for the analysis of thermodynamic stability of the enzyme by measuring the binding affinity and stoichiometry.[1] The enzyme has also been used to generate CD4+ T cell lines specific for carbonic anhydrase during the study of autoimmune pancreatitis in rat.[2]
Biochem/physiol Actions
Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in many physiological and pathological processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, inhibitors that block this enzyme can have therapeutic implications in glaucoma, epilepsy and Parkinson′s disease.[1]
Other Notes
One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0 °C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)
1 of 1
This Item | |||
|---|---|---|---|
| specific activity ≥3,000 W-A units/mg protein | specific activity ≥2,000 W-A units/mg protein | specific activity ≥3,500 W-A units/mg protein | specific activity ≥3,000 W-A units/mg protein |
| biological source bovine erythrocytes | biological source - | biological source bovine erythrocytes | biological source - |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
| mol wt 30 kDa | mol wt - | mol wt - | mol wt 30 kDa |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
Still not finding the right product?
Explore all of our products under Carbonic Anhydrase Isozyme II from bovine erythrocytes
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Rui Hou et al.
ACS omega, 8(21), 19057-19071 (2023-06-05)
DNA-encoded library (DEL) is a powerful ligand discovery technology that has been widely adopted in the pharmaceutical industry. DEL selections are typically performed with a purified protein target immobilized on a matrix or in solution phase. Recently, DELs have also
Arne Schön et al.
Analytical biochemistry, 488, 45-50 (2015-08-05)
Protein aggregation is a major issue affecting the long-term stability of protein preparations. Proteins exist in equilibrium between the native and denatured or partially denatured conformations. Often denatured or partially denatured conformations are prone to aggregate because they expose to
Gérard Liger-Belair et al.
ACS omega, 8(25), 22844-22853 (2023-07-03)
When it comes to champagne tasting, dissolved CO2 is a key compound responsible for the very much sought-after effervescence in glasses. Nevertheless, the slow decrease of dissolved CO2 during prolonged aging of the most prestigious cuvees raises the issue of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C2522-5MG | 04061833484159 |
| C2522-100MG | 04061833484135 |
| C2522-25MG | 04061833484142 |