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8.08259

2,2,2-Trifluoroethanol

for synthesis

Synonym(s):

2,2,2-Trifluoroethanol

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About This Item

Empirical Formula (Hill Notation):
C2H3F3O
CAS Number:
Molecular Weight:
100.04
UNSPSC Code:
12352104
EC Index Number:
200-913-6
NACRES:
NA.22
MDL number:
Assay:
≥99% (GC)
Grade:
synthesis grade
Bp:
73.6 °C/1013 hPa
Vapor pressure:
70.9 hPa ( 20 °C)
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grade

synthesis grade

Quality Level

vapor pressure

70.9 hPa ( 20 °C)

assay

≥99% (GC)

form

liquid

potency

240 mg/kg LD50, oral (Rat), 1680 mg/kg LD50, skin (Rat)

expl. lim.

8.4-28.8 % (v/v)

dilution

(for synthesis)

pH

7

bp

73.6 °C/1013 hPa

mp

-43.5 °C

transition temp

flash point 30 °C

density

1.38 g/cm3 at 25 °C

storage temp.

2-30°C

SMILES string

FC(F)(F)CO

InChI

1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

InChI key

RHQDFWAXVIIEBN-UHFFFAOYSA-N

General description

2,2,2-Trifluoroethanol (TFE) is a fluorinated compound used as a solvent in organic synthesis. Peptides and proteins are experimentally studied using TEE as a cosolvent. In TFE, hydrogen peroxide is effective for oxidizing sulfur compounds.

Application

2,2,2-Trifluoroethanol is used as a solvent:
  • In the preparation of nylon/Ag composite nanofibers by electrospinning method.
  • To study the combination of two polymers PANI (polyaniline) and PHB (polyhydroxy-butyrate).

Features and Benefits

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

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This Item
T6300291683426237
Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

grade

synthesis grade

grade

-

grade

analytical standard

grade

-

assay

≥99% (GC)

assay

≥99%

assay

≥99.5% (GC)

assay

99% (CP)

form

liquid

form

liquid

form

-

form

liquid

mp

-43.5 °C

mp

−44 °C (lit.)

mp

−44 °C (lit.)

mp

−44 °C (lit.)

vapor pressure

70.9 hPa ( 20 °C)

vapor pressure

70 mmHg ( 25 °C)

vapor pressure

70 mmHg ( 25 °C)

vapor pressure

-


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Blood

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

86.0 °F - closed cup

flash_point_c

30 °C - closed cup



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
808259010004022536398624
808259100004022536894799
808259025004022536398631

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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