Iodine content is not a specification for product release and has not been characterized.
T6830
Thyroglobulin human
Synonym(s):
Thyroglobulin human
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About This Item
Form:
lyophilized solid
Assay:
≥95% (SDS-PAGE)
Biological source:
human
Pricing and availability is not currently available.
General description
Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Graves′ disease, frequently develop antibodies against human Thyroglobulin. Thryoglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and in Graves′ disease.
Biochem/physiol Actions
Thyroglobulin has been shown to induce expression of platelet activating factor in human peripheral blood mononuclear cells which is found elevated in some patients with thyroid disease. [1]
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This Item | |||
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay ≥95% (PAGE) | assay - | assay ≥90% (SDS-PAGE) |
| biological source human | biological source human thyroid | biological source - | biological source bovine thyroid |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) liquid chromatography (LC): suitable | technique(s) - |
| form lyophilized solid | form lyophilized | form liquid | form lyophilized solid |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - | UniProt accession no. - |
| Gene Information human ... TG(7038) | Gene Information - | Gene Information - | Gene Information - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E Resetkova et al.
Regional immunology, 4(4), 204-208 (1992-07-01)
Platelet activating factor (PAF), a phospholipid mediator, has been found to play a role in immune reactions, as well as in many pathophysiological alterations in certain disorders. To determine whether there might be a potential role of PAF in the
Ricardo Adaixo et al.
Nature communications, 13(1), 61-61 (2022-01-12)
The thyroglobulin (TG) protein is essential to thyroid hormone synthesis, plays a vital role in the regulation of metabolism, development and growth and serves as intraglandular iodine storage. Its architecture is conserved among vertebrates. Synthesis of triiodothyronine (T3) and thyroxine
Pengfei Zhang et al.
Nature communications, 13(1), 2298-2298 (2022-04-29)
Evanescent illumination has been widely used to detect single biological macromolecules because it can notably enhance light-analyte interaction. However, the current evanescent single-molecule detection system usually requires specially designed microspheres or nanomaterials. Here we show that single protein detection and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T6830-1MG | 04061826704165 |
| T6830-5MG | 04061833226902 |
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Hello, Does the product "Thyroglobulin Human", T6830, contain any iodine? or is it free from iodine? There is no specification stating any percentage of iodine present in the protein. Thanks!
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