B4679

BIS-TRIS propane

BioPerformance Certified, suitable for cell culture, ≥99.0%

• Synonym(s): 1,3-Bis[tris(hydroxymethyl)methylamino]propane
• Linear Formula: CH₂[CH₂NHC(CH₂OH)₃]₂
• CAS Number: 64431-96-5
• Molecular Weight: 282.33
• UNSPSC Code: 12161700
• NACRES: NA.25
• PubChem Substance ID: 24891799
• EC Number: 264-899-3
• Beilstein/REAXYS Number: 1786109
• MDL number: MFCD00004689

Properties

• grade: BioPerformance Certified
• Quality Segment: 400
• assay: ≥99.0%
• form: crystals
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin and bioburden, tested
• useful pH range: 6.3-9.5
• pKa (25 °C): (1) 6.8, (2) 9.0
• mp: 164-165 °C (lit.)
• application(s): diagnostic assay manufacturing
• foreign activity: DNAse (exonuclease), NICKase (endonuclease), RNAse, and protease, none detected
• SMILES string: OCC(CO)(CO)NCCCNC(CO)(CO)CO
• InChI: 1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
• InChI key: HHKZCCWKTZRCCL-UHFFFAOYSA-N

Description

Application

• Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor.: BIS-TRIS propane is used in the development of nanowire field-effect transistors for detecting GC-rich RNA sequences. The study demonstrates the buffer′s role in enhancing the specificity and sensitivity of these biosensors (Chou et al., 2019).


• Elimination of ghost peaks by optimization of anion exchange chromatography method for determination of gamma-carboxyglutamic acid (Gla)-domainless impurity in recombinant activated clotting factor VII drug products.: BIS-TRIS propane is employed in optimizing chromatography methods to eliminate ghost peaks during the analysis of pharmaceutical impurities. The buffer′s effectiveness ensures accurate and reliable detection of impurities in drug formulations (Tahmasbi et al., 2019).

Other Notes

Easily compare specifications for BIS-TRIS propane products with the BIS-TRIS propane specification table.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)