A4638

Azathioprine

synthetic (organic), ≥98%, DNA/RNA synthesis disruptor, powder

• Synonym(s): 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
• Empirical Formula (Hill Notation): C₉H₇N₇O₂S
• CAS Number: 446-86-6
• Molecular Weight: 277.26
• NACRES: NA.77
• PubChem Substance ID: 57653853
• UNSPSC Code: 12352202
• EC Number: 207-175-4
• MDL number: MFCD00069203

Properties

• Product Name: Azathioprine, ≥98%
• biological source: synthetic (organic)
• Quality Segment: 100
• assay: ≥98%
• form: powder
• solubility: 1 M NH4OH: 20 mg/mL, clear to slightly hazy
• storage temp.: −20°C
• SMILES string: Cn1cnc(c1Sc2ncnc3[nH]cnc23)[N+]([O-])=O
• InChI: 1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)
• InChI key: LMEKQMALGUDUQG-UHFFFAOYSA-N
• Gene Information: human ... PPAT(5471)

Description

Biochem/physiol Actions

Has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders.[1]

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H315,H319,H335,H350,H361fd
• pcodes: P202 - P261 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges