Skip to Content
Merck

Key Documents

View All Documentation

Skip To

90182

Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride

≥99.0% (AT)

Synonym(s):

(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, (3S)-7-Amino-1-chloro-3-tosylamino-2-heptanone hydrochloride, TLCK, Tosyl-L-lysyl-chloromethane hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice

About This Item

Empirical Formula (Hill Notation):
C14H21ClN2O3S · HCl
CAS Number:
4272-74-6
Molecular Weight:
369.31
NACRES:
NA.77
PubChem Substance ID:
57653369
eCl@ss:
32160406
UNSPSC Code:
12352202
EC Number:
224-266-4
MDL number:
MFCD00065395
Beilstein/REAXYS Number:
7106867
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

synthetic

Quality Segment

100

assay

≥99.0% (AT)

form

powder or crystals

optical activity

[α]20/D −7.8±0.5°, c = 2% in H2O

storage temp.

−20°C

SMILES string

Cl[H].Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl

InChI

1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1

InChI key

YFCUZWYIPBUQBD-ZOWNYOTGSA-N

Other Notes

An alkylating reagent that may react with histidine or cysteine residues at the active site of enzymes. Inactivates serine proteases such as trypsin [1][2][3] and clostripain [4]. Chymotrypsin is not affected. To prevent proteolytic degradation, a combination of TLCK and TPCK can be used throughout the isolation of proteins, as in the isolation of histones.[5]

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
T7254T437621612
Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥99.0% (AT)

Sigma-Aldrich

90182

Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride

Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride ≥96% (TLC), powder

Sigma-Aldrich

T7254

Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride

N-p-Tosyl-L-phenylalanine chloromethyl ketone ≥97% (TLC), powder

Sigma-Aldrich

T4376

N-p-Tosyl-L-phenylalanine chloromethyl ketone

L-(−)-α-Amino-ε-caprolactam hydrochloride ≥97.0% (AT)

Sigma-Aldrich

21612

L-(−)-α-Amino-ε-caprolactam hydrochloride

assay

≥99.0% (AT)

assay

≥96% (TLC)

assay

≥97% (TLC)

assay

≥97.0% (AT)

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic

biological source

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

powder or crystals

form

powder

form

powder

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

optical activity

[α]20/D −7.8±0.5°, c = 2% in H2O

optical activity

-

optical activity

-

optical activity

[α]20/D −27±2°, c = 1% in H2O

Still not finding the right product?

Explore all of our products under Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1B

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCL8593
BCCL6102
BCCL6681
BCCK7268
BCCL1911

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
90182-500MG04061833267325
90182-100MG04061833246443

Questions

Reviews

No rating value

Active Filters