41707
2-C-Methyl-D-erythritol
≥90% (GC)
Synonym(s):
(2S,3R)-2-Methyl-1,2,3,4-tetrahydroxybutane, (2S,3R)-2-Methylbutane-1,2,3,4-tetrol
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About This Item
Empirical Formula (Hill Notation):
C5H12O4
CAS Number:
Molecular Weight:
136.15
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5916602
Pricing and availability is not currently available.
biological source
(Carum ajowan fruit)
Quality Level
assay
≥90% (GC)
form
viscous liquid (clear)
color
colorless
storage temp.
2-8°C
SMILES string
C[C@](O)(CO)[C@H](O)CO
InChI
1S/C5H12O4/c1-5(9,3-7)4(8)2-6/h4,6-9H,2-3H2,1H3/t4-,5+/m1/s1
InChI key
HGVJFBSSLICXEM-UHNVWZDZSA-N
General description
(2S,3R)-2-methylbutane-1,2,3,4-tetrol was identified as a glucide in methanol extracts of Carum ajowan fruit.
Biochem/physiol Actions
Metabolite of the non-mevalonate MEP pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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This Item | |||
|---|---|---|---|
| assay ≥90% (GC) | assay ≥99% (GC) | assay ≥75% (TLC) | assay - |
| biological source (Carum ajowan fruit) | biological source - | biological source - | biological source - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| form viscous liquid (clear) | form powder | form syrup | form - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| color colorless | color white | color colorless to very dark yellow | color - |
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Gur Pines et al.
Molecules (Basel, Switzerland), 25(9) (2020-05-15)
Drug resistance is a major healthcare challenge, resulting in a continuous need to develop new inhibitors. The development of these inhibitors requires an understanding of the mechanisms of resistance for a critical mass of occurrences. Recent genome editing technologies based
Incorporation of 2-C-methyl-D-erythritol, a putative isoprenoid precursor in the mevalonate-independent pathway, into ubiquinone and menaquinone of Escherichia coli.
Duvold, T., et al.
Tetrahedron Letters, 38, 6181-6184 (1997)
Jin-Zheng Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(1), 355-361 (2019-12-28)
The methylerythritol phosphate (MEP) pathway is responsible for producing isoprenoids, metabolites with essential functions in the bacterial kingdom and plastid-bearing organisms including plants and Apicomplexa. Additionally, the MEP-pathway intermediate methylerythritol cyclodiphosphate (MEcPP) serves as a plastid-to-nucleus retrograde signal. A suppressor
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 41707-5MG | 04061832090061 |