1605500

Ropivacaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Ropivacaine hydrochloride monohydrate, (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride monohydrate, (S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride monohydrate, Naropin hydrochloride monohydrate
• Empirical Formula (Hill Notation): C₁₇H₂₆N₂O · HCl · H₂O
• CAS Number: 132112-35-7
• Molecular Weight: 328.88
• NACRES: NA.24
• PubChem Substance ID: 329751059
• UNSPSC Code: 41116107
• MDL number: MFCD00946578

Properties

• grade: pharmaceutical primary standard
• API family: ropivacaine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: O.Cl.CCCN1CCCC[C@H]1C(=O)Nc2c(C)cccc2C
• InChI: 1S/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2/t15-;;/m0../s1
• InChI key: VSHFRHVKMYGBJL-CKUXDGONSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ropivacaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Fentanyl Citrate and Ropivacaine Hydrochloride Compounded Injection
• Ropivacaine Hydrochloride
• Ropivacaine Hydrochloride Injection

Biochem/physiol Actions

Local anaesthetic with less cardiotoxicity than bupivacaine.

Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable