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2-tert-Butyl-4-hydroxyanisole

Name: 2-<I>tert</I>-Butyl-4-hydroxyanisole
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-BHA, 3-(1,1-Dimethylethyl)-4-methoxyphenol, 3-tert-Butyl-4-methoxyphenol

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₆O₂

CAS Number:

88-32-4

Molecular Weight:

180.24

MDL number:

MFCD00057667

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

butylhydroxyanisole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O(C)c1c(cc(cc1)O)C(C)(C)C

InChI

1S/C11H16O2/c1-11(2,3)9-7-8(12)5-6-10(9)13-4/h5-7,12H,1-4H3

InChI key

IMOYOUMVYICGCA-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

2-tert-Butyl-4-hydroxyanisole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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1 of 1

This Item	PHR2336	PHR1306	20021
USP 1083008 2-tert-Butyl-4-hydroxyanisole	Supelco PHR2336 2-tert-Butyl-4-hydroxyanisole	Supelco PHR1306 3-tert-Butyl-4-hydroxyanisole	Sigma-Aldrich 20021 3-tert-Butyl-4-hydroxyanisole
grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard	grade -
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical small molecule	application(s) pharmaceutical (small molecule)	application(s) -
format neat	format -	format neat	format -
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-30°C	storage temp. -
API family butylhydroxyanisole	API family butylhydroxyanisole	API family bha	API family -

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Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Modulation by dietary factors of BHA-induced alterations in cell kinetics of gastro-intestinal tract tissues in rats.

P A Schilderman et al.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 29(2), 79-85 (1991-02-01)

To determine the effects of dietary ethanol or fibre on 2(3)-tert-butyl-4-hydroxyanisole (BHA)-induced alterations in cell kinetics in gastro-intestinal tract tissues, groups of six male Wistar rats were fed diets containing 0% (control) or 1.5% BHA for 2 wk. One group

Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases.

H Nishiya et al.

Pharmacology, 39(4), 213-223 (1989-01-01)

Binding of cefpiramide (CPM) and other beta-lactam antimicrobial agents to 2(3)-tert-butyl-4-hydroxyanisole (BHA)-induced liver glutathione (GSH) S-transferases (EC 2.5.1.18) from CD-1 mice was studied. A marked induction of hepatic GSH S-transferase from mice fed BHA was observed. Gel chromatography of liver

Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C.

Laura Romero et al.

Molecular pharmacology, 70(1), 277-286 (2006-04-13)

The regulation of human GSTA1 by chemical inducers of rodent glutathione S-transferases (GSTs) and the regulatory role of hepatic nuclear factor (HNF) 1 was investigated in Caco-2 cells. Treatment of preconfluent and confluent cells with 12-O-tetra-decanoyl phorbol-13-acetate (TPA), 3-methylcholanthrene (3-MC)

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Global Trade Item Number

SKU	GTIN
1083008-200MG	04061838682550

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