E6005

Ethionamide

≥98.0%, suitable for ligand binding assays

• Synonym(s): 2-Ethyl-4-pyridinecarbothioamide
• Empirical Formula (Hill Notation): C₈H₁₀N₂S
• CAS Number: 536-33-4
• Molecular Weight: 166.24
• EC Number: 208-628-9
• MDL number: MFCD00057361
• UNSPSC Code: 12352111
• PubChem Substance ID: 24894350
• NACRES: NA.26

Properties

• product name: Ethionamide,
• Assay: ≥98.0%
• form: powder
• technique(s): ligand binding assay: suitable
• color: yellow
• storage temp.: 2-8°C
• SMILES string: CCc1cc(ccn1)C(N)=S
• InChI: 1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)
• InChI key: AEOCXXJPGCBFJA-UHFFFAOYSA-N

Description

General description

Ethionamide (ETA, ETH), a thioamide, is an anti-tuberculosis agent used as a second-line therapy in treating tuberculosis when other agents are not effective. The structure of ETA is similar to isoniazid.

Application

Ethionamide is used in antimicrobials and in potency assay of test compounds on M. tuberculosis.

Biochem/physiol Actions

Ethionamide is used as an anti-tuberculosis antibiotic and an inducer of hypothyroidism.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H361
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves