We have not found this to be suitable for PCR. This product is soluble in water (50 mg/ml), yielding a clear, colorless solution. The solubility of this product in water has also been reported at 64.7 g/100ml (25 °C). It is soluble at 5.0 g/100 mL in ethanol. It is practically insoluble in chloroform and in ether. The pH of a 5% aqueous solution of this product is 1.0
B3501
Betaine hydrochloride
synthetic (organic), ≥99%, osmoprotectant, powder or crystals
Synonym(s):
(Carboxymethyl)trimethylammonium hydrochloride
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About This Item
Linear Formula:
(CH3)3N+CH2COOH · Cl-
CAS Number:
Molecular Weight:
153.61
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
209-683-1
MDL number:
Beilstein/REAXYS Number:
3916181
Pricing and availability is not currently available.
Product Name
Betaine hydrochloride, ≥99%
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
powder or crystals
mp
241-242 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
[Cl-].C[N+](C)(C)CC(O)=O
InChI
1S/C5H11NO2.ClH/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H
InChI key
HOPSCVCBEOCPJZ-UHFFFAOYSA-N
Gene Information
human ... BHMT(635), BHMT2(23743)
General description
Betaine (trimethyl glycine) is an osmoprotectant, which is highly effective than proline. It is formed in from choline. Betaine is usually present in grains, spinach, beets, broccoli, shellfish and marine algae.
Application
Betaine hydrochloride has been used as a component of fixative in HEPES or cacodylate buffer to improve preservation of the ultrastructural morphology of human spermatozoa.
Biochem/physiol Actions
Betaine hydrochloride can decrease hepatotoxicity, that is stimulated by ethanol.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.
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This Item | |||
|---|---|---|---|
| assay ≥99% | assay - | assay - | assay - |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| Gene Information human ... BHMT(635), BHMT2(23743) | Gene Information human ... BHMT(635), BHMT2(23743) | Gene Information - | Gene Information - |
| Quality Level 100 | Quality Level - | Quality Level 300 | Quality Level 200 |
| form powder or crystals | form - | form powder | form crystals |
| solubility water: 50 mg/mL, clear, colorless | solubility - | solubility - | solubility 647 g/L |
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Effect of drying medium on the viability of dried
Selmer OE, et al.
Immobilized Cells: Basics and Applications, 11, 229-229 (1996)
Can Phytochemicals be Effective in Preventing Ethanol-Induced Hepatotoxicity in the Geriatric Population? An Evidence-Based Revisit
Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults, 163- 170 (2015)
Improved preservation of ultrastructural morphology in human spermatozoa using betaine in the primary fixative
Swan MA
International Journal of Andrology, 20(1), 45- 54 (1997)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B3501-1KG | 04061833428078 |
| B3501-100G | 04061833428061 |
| B3501-250G | 04061833428085 |
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Hi! I have two questions about betaine hydrochloride: 1. Can it be used in PCR like betaine?; 2. Why is it hard to dissolve at 5M, and how can I fix this? Thanks for your help!
1 answer-
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