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A5752

Adrenochrome

>95% purity (HPLC), powder

Synonym(s):

3-Hydroxy-1-methyl-5,6-indolinedione

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About This Item

Empirical Formula (Hill Notation):
C9H9NO3
CAS Number:
Molecular Weight:
179.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
200-192-8
MDL number:
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Product Name

Adrenochrome, ≥95% (HPLC)

Quality Level

assay

≥95% (HPLC)

form

powder

color

red to brown

εmax

3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CN1CC(O)C2=CC(=O)C(=O)C=C12

InChI

1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3

InChI key

RPHLQSHHTJORHI-UHFFFAOYSA-N

Application

Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.

Biochem/physiol Actions

Adrenochrome is an oxidation product of adrenaline. It has been implicated in cardiotoxicity. It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria. Adrenochrome is also suggested to exhibit psychotomimetic effects. It is used to determine superoxide dismutase activity.

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This Item
214515D7008N5625
color

red to brown

color

-

color

pink to very dark red

color

-

form

powder

form

powder

form

powder

form

powder

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

assay

≥95% (HPLC)

assay

-

assay

≥95%

assay

>99% (TLC)

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Effect of Bacillus coagulans and B. firmus incorporated probiotic diet on Superoxide dismutase activity and catalase activity in Penaeus monodon.
Raghu P, et al.
World Scientific News, 44, 224-224 (2016)
Cardiotoxicity of adrenochrome in isolated rabbit hearts assessed by epicardial NADH fluorescence.
Rump AF, et al.
Archives of Toxicology, 68, 571-571 (1994)
Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate.
Molinnus D, et al.
Sensors and Actuators B, Chemical, 237, 190-195 (2016)



Global Trade Item Number

SKUGTIN
A5752-25MG04061832339986
A5752-250MG04061832339979

Questions

1–2 of 2 Questions  
  1. has there been any studies between this and anti aging or cell revitalisation?

    1 answer
    1. The Adrenochrome available for sale is only intended for Research Use Only. There have been no clinical studies performed using A5752. There are varied uses for Adrenochrome. The website has a list of some 40 Peer Reviewed Papers for various uses. A quick review of the available abstracts did not reveal papers that were specific for either anti aging or cell revitalization. There would probably be additional reference papers available on the PubMed website.

      Helpful?

  2. Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?

    1 answer
    1. This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
      https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005

      Helpful?

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