Unfortunately, this product is not tested for sterility or endotoxin. Currently, a sterile, endotoxin-tested solution is not available.
T9326
Thrombin human
BioUltra, recombinant, expressed in HEK 293 cells, aqueous solution, ≥95% (SDS-PAGE)
Synonym(s):
Factor IIa
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About This Item
Specific activity:
≥2,000 units/mg protein
Assay:
≥95% (SDS-PAGE)
Recombinant:
expressed in HEK 293 cells
Pricing and availability is not currently available.
General description
Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.
Application
Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess in vitro hemostatic properties of French lyophilized plasma. [1]
Physical form
supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride
Other Notes
Activity is expressed in NIH units obtained by direct comparison to a NIH thrombin reference standard.
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This Item | |||
|---|---|---|---|
| specific activity ≥2,000 units/mg protein | specific activity ≥2800 NIH units/mg protein (E1%/280, 18.3) | specific activity - | specific activity - |
| Gene Information human ... F2(2147) | Gene Information human ... F2(2147) | Gene Information human ... F2(2147) | Gene Information human ... F2(2147) |
| assay ≥95% (SDS-PAGE) | assay - | assay ≥95% (SDS-PAGE) | assay - |
| recombinant expressed in HEK 293 cells | recombinant - | recombinant - | recombinant - |
| form aqueous solution | form lyophilized powder | form lyophilized | form lyophilized powder |
| mol wt 37.4 kDa | mol wt 37.4 kDa | mol wt 37 kDa | mol wt - |
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Related Content
Instructions
Christophe Martinaud et al.
Anesthesiology, 117(2), 339-346 (2012-06-29)
French lyophilized plasma (FLyP) is used routinely by the French Armed Forces in war settings. The authors compared concentrations of coagulation proteins and global in vitro hemostatic properties in FLyP and in the same plasma before lyophilization to assess the
Katerina Zakharova et al.
International journal of molecular sciences, 22(14) (2021-07-25)
Redβ is a 261 amino acid protein from bacteriophage λ that promotes a single-strand annealing (SSA) reaction for repair of double-stranded DNA (dsDNA) breaks. While there is currently no high-resolution structure available for Redβ, models of its DNA binding domain
Ute Metzger et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14309-14314 (2009-08-27)
Ergot alkaloids are toxins and important pharmaceuticals that are produced biotechnologically on an industrial scale. The first committed step of ergot alkaloid biosynthesis is catalyzed by dimethylallyl tryptophan synthase (DMATS; EC 2.5.1.34). Orthologs of DMATS are found in many fungal
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T9326-150UN | 04061837381270 |
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Hello, is the product sterile or tested for content of endotoxin? Kind regards,
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