T8761

Tyloxapol

nonionic surfactant

• Synonym(s): 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane
• CAS Number: 25301-02-4
• MDL number: MFCD00149002
• UNSPSC Code: 12161900
• PubChem Substance ID: 24900557
• NACRES: NA.25

Properties

• CMC: 0.018 mM
• transition temp: cloud point 94.3 °C
• SMILES string: [H]C([H])=O.OCCO.CC(C)(C)CC(C)(C)c1ccc(O)cc1
• InChI: 1S/C14H22O.C2H6O2.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;3-1-2-4;1-2/h6-9,15H,10H2,1-5H3;3-4H,1-2H2;1H2
• InChI key: GWJOFBXSBDVUMH-UHFFFAOYSA-N

Description

General description

A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Used as a surfactant.

Application

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction. Tyloxapol is used in the development of non-ionic surfactant-based liposomes (niosomes) for use in drug delivery systems. Tyloxapol may be used to study its mechanism of protecting macrophages from endotoxins. Tyloxapol may be used to study is potential cell toxicitiy.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves