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T3376

DL-α-Tocopherol acetate

≥96% (HPLC)

Synonym(s):

Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
7695-91-2
Molecular Weight:
472.74
UNSPSC Code:
12352205
NACRES:
NA.79
PubChem Substance ID:
24900133
EC Number:
231-710-0
Beilstein/REAXYS Number:
97512
MDL number:
MFCD00072042
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biological source

synthetic (organic)

Quality Level

200

assay

≥96% (HPLC)

form

viscous liquid

technique(s)

HPLC: suitable

color

colorless to dark yellow

density

0.96 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

General description

α-Tocopherol is a predominant form of vitamin E in human and animal tissues and also in leaf chloroplasts. It is the major form in supplements. DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.

Application

DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats. It has also been used as a standard in α-tocopherol analysis using plasma sample and mature fresh tobacco leaves.[1]

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

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This Item
2999292359T1600000
DL-α-Tocopherol acetate ≥96% (HPLC)

Sigma-Aldrich

T3376

DL-α-Tocopherol acetate

DL-α-Tocopherol acetate tested according to Ph. Eur.

Sigma-Aldrich

29992

DL-α-Tocopherol acetate

DL-α-Tocopherol acetate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

92359

DL-α-Tocopherol acetate

α-Tocopherol acetate European Pharmacopoeia (EP) Reference Standard

T1600000

α-Tocopherol acetate

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

biological source

synthetic (organic)

biological source

synthetic

biological source

-

biological source

synthetic

assay

≥96% (HPLC)

assay

96.5-102.0%

assay

-

assay

-

form

viscous liquid

form

liquid

form

viscous liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

-

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000551856
0000551856
WXBF8503V
MKDB7255
0000499458

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Related Content

Nutrient Requirements of Fish and Shrimp (2011)
High levels of dietary unsaturated fat decrease alpha-tocopherol content of whole body, liver, and plasma of chickens without variations in intestinal apparent absorption
Villaverde C, et al.
Poultry Science, 87(3), 497-505 (2008)
Effect of alpha-tocopherol supplementation on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus in spontaneously hypertensive rats
da Costa VAV and Vianna LM
Clinica Chimica Acta; International Journal of Clinical Chemistry, 351(1-2), 101-104 (2005)
View All Related Papers

Global Trade Item Number

SKUGTIN
T3376-5G04061835549993
T3376-100G04061835549986
T3376-25G04061835522620

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the concentration?

    1 answer

    1. This product is a neat or pure liquid and has not been diluted. The concentration may be determined by using the lot specific purity reported in the Certificate of Analysis, the density, and the compound molecular weight. This product has a density of 0.96 g/mL and a molecular weight of 472.74 g/mol. The minimum purity is 96%, thus the molarity will vary slightly from lot to lot. The molarity can range from 1.95M (96%) to 2.03M (100%). Please see the link below to review the product datasheet for additional information.
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/295/556/t3376pis.pdf

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