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D-(−)-3-Phosphoglyceric acid disodium salt

Name: <SC>D-</SC>(−)-3-Phosphoglyceric acid disodium salt
Brand: SIGMA

≥93% dry basis (enzymatic), powder

Synonym(s):

(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt

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About This Item

Empirical Formula (Hill Notation):

C₃H₅Na₂O₇P

CAS Number:

80731-10-8

Molecular Weight:

230.02

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24898988

MDL number:

MFCD00069569

Beilstein/REAXYS Number:

3767836

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Properties

biological source

synthetic (inorganic)

Quality Level

200

assay

≥93% dry basis (enzymatic)

form

powder

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sustainability

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impurities

<14% water (NMR)

color

white

solubility

H₂O: 50 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 18-22% (dry basis)

greener alternative category

Re-engineered,

storage temp.

−20°C

SMILES string

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1

InChI key

RGCJWQYUZHTJBE-YBBRRFGFSA-L

Description

Application

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. [1] It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis. [2]

Biochem/physiol Actions

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item	D5764	P6888	P7877
Sigma-Aldrich P8877 D-(−)-3-Phosphoglyceric acid disodium salt	Sigma-Aldrich D5764 2,3-Diphospho-D-glyceric acid pentasodium salt	Sigma-Aldrich P6888 6-Phosphogluconic acid trisodium salt	Sigma-Aldrich P7877 6-Phosphogluconic acid trisodium salt
assay ≥93% dry basis (enzymatic)	assay -	assay ≥95% anhydrous basis	assay ≥97% (enzymatic)
biological source synthetic (inorganic)	biological source synthetic	biological source synthetic (inorganic)	biological source synthetic (organic)
solubility H₂O: 50 mg/mL, clear, colorless to faintly yellow	solubility water: 100 mg/mL, clear, colorless to faintly yellow	solubility water: 50 mg/mL, clear, colorless	solubility water: 50 mg/mL, clear, colorless
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H315,H319,H335,H371

pcodes

P260 - P264 - P271 - P302 + P352 - P305 + P351 + P338 - P308 + P311

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

Storage Class

11 - Combustible Solids

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Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

Balázs Németi et al.

Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)

Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in

Phosphorylation of glyceric acid in aqueous solution using trimetaphosphate.

V Kolb et al.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)

The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5

Evolution of bacterial phosphoglycerate mutases: non-homologous isofunctional enzymes undergoing gene losses, gains and lateral transfers.

Jeremy M Foster et al.

PloS one, 5(10), e13576-e13576 (2010-12-29)

The glycolytic phosphoglycerate mutases exist as non-homologous isofunctional enzymes (NISE) having independent evolutionary origins and no similarity in primary sequence, 3D structure, or catalytic mechanism. Cofactor-dependent PGM (dPGM) requires 2,3-bisphosphoglycerate for activity; cofactor-independent PGM (iPGM) does not. The PGM profile

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Global Trade Item Number

SKU	GTIN
P8877-1G	04061834401988
P8877-10MG	04061834401971
P8877-5G	04061834402008

Questions

1–2 of 2 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
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Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
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