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F2878

Ficoll® PM 70

Type 70

Ficoll® PM 70

Synonym(s):

Poly(sucrose-co-epichlorhydrin)

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
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type

Type 70

Quality Segment

form

powder

mol wt

~70,000

color

white

solubility

H2O: soluble 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

General description

Ficoll® PM70, a high molecular weight branched polysaccharide polymer, is believed that they do not contain any ionized groups. This sucrose-polymer is formed by the copolymerization of sucrose with epichlorhydrin.

Application

Ficoll® PM 70 has been used:
  • as a macromolecule in a comparative study to evaluate its effect in vitrification solutions
  • as a supplement in the vitrification solution for the vitrification procedure of oocytes
  • as a component of low serum medium for human lung fibroblast cell culture to promote a crowded environment

Biochem/physiol Actions

Ficoll is commonly used as a macromolecular constituent of vitrification solutions. Due to their dense branching, Ficolls also serve as ideal, nearly spherical molecular crowding agents.
FicollTM PM 70 is used as a macromolecular crowding agent in studies of cell volume signaling and protein refolding.[1]It may be used in tissue engineering and macromolecular conformation research for the development, evaluation, and use of macromolecular crowding (MMC) systems and configurations. Ficoll PM-70 can also be used in vitrification research.

Other Notes

A nonionic synthetic polymer of sucrose.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

Ficoll is a registered trademark of Cytiva

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This Item
GE17-0310-10GE17-0300-10GE17-0310-50
Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

solubility

H2O: soluble 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

soluble

solubility

soluble

solubility

soluble

form

powder

form

solid, spray-dried

form

solid, spray-dried

form

solid, spray-dried

color

white

color

White

color

White

color

White

mol wt

~70,000

mol wt

60-80 kDa

mol wt

-

mol wt

60-80 kDa

type

Type 70

type

-

type

-

type

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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