E6005

Ethionamide

≥98.0%, suitable for ligand binding assays

• Synonym(s): 2-Ethyl-4-pyridinecarbothioamide
• Empirical Formula (Hill Notation): C₈H₁₀N₂S
• CAS Number: 536-33-4
• Molecular Weight: 166.24
• NACRES: NA.26
• PubChem Substance ID: 24894350
• UNSPSC Code: 12352111
• EC Number: 208-628-9
• MDL number: MFCD00057361

Properties

• Product Name: Ethionamide,
• assay: ≥98.0%
• Quality Segment: 200
• form: powder
• technique(s): ligand binding assay: suitable
• color: yellow
• storage temp.: 2-8°C
• SMILES string: CCc1cc(ccn1)C(N)=S
• InChI: 1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)
• InChI key: AEOCXXJPGCBFJA-UHFFFAOYSA-N

Description

General description

Ethionamide (ETA, ETH), a thioamide,[1] is an anti-tuberculosis agent used as a second-line therapy in treating tuberculosis when other agents are not effective.[2][3][4] The structure of ETA is similar to isoniazid.

Application

Ethionamide is used in antimicrobials[5] and in potency assay of test compounds on M. tuberculosis.[6]

Biochem/physiol Actions

Ethionamide is used as an anti-tuberculosis antibiotic and an inducer of hypothyroidism.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges