The enantiomeric purity of this compound is not a product specification determined for batch release. However, the range of optical rotation value needed for batch release, as indicated in the lot specific Certificate of Analysis, is very close to the published literature value for the (-) enantiomer (Org Lett. 2005 Sep 15;7(19):4181-3).
C1112
CP-55940
>98% (HPLC), cannabinoid receptor agonist, powder
Synonym(s):
5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
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About This Item
Empirical Formula (Hill Notation):
C24H40O3
CAS Number:
Molecular Weight:
376.57
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
>98% (HPLC)
Form:
powder
Storage condition:
desiccated
Pricing and availability is not currently available.
Product Name
CP-55940, >98% (HPLC), powder
Quality Segment
assay
>98% (HPLC)
form
powder
optical activity
[α]/D -24 to -30°, c = 0.2 in chloroform-d
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
storage condition
desiccated
solubility
DMSO: 15 mg/mL, H2O: slightly soluble
storage temp.
2-8°C
SMILES string
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
InChI
1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
InChI key
YNZFFALZMRAPHQ-SYYKKAFVSA-N
Gene Information
human ... CNR1(1268), CNR2(1269)
rat ... Cnr1(25248)
Application
CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).
Biochem/physiol Actions
CP-55940 is a selective cannabinoid receptor agonist.
CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.
Features and Benefits
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| assay >98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| drug control regulated under CDSA - not available from Sigma-Aldrich Canada | drug control - | drug control - | drug control - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition desiccated | storage condition desiccated | storage condition - | storage condition desiccated |
signalword
Warning
hcodes
Hazard Classifications
STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| C1112-10MG | 04061833460788 |
| C1112-50MG | 04061833460795 |
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Can you please specify whether C1112 (CP 55,940) is a +, a -, or +/- (racemic) enantiomer?
1 answer-
Helpful?
-
-
Could you please specify whether C1112 (CP 55,940) is a +, a -, or +/- (racemic) enantiomer? Thank you!
1 answer-
The enantiomeric purity of this compound is not a product specification determined for batch release. However, the range of optical rotation required for batch release, as indicated in the lot-specific Certificate of Analysis, is very close to the published literature value for the (-) enantiomer.
Org Lett. 2005 Sep 15;7(19):4181-3.
Helpful?
-