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nor-Binaltorphimine Dihydrochloride

Name: nor-Binaltorphimine Dihydrochloride
Brand: MM

≥98% (HPLC), solid, κ-opioid receptor antagonist, Calbiochem

Synonym(s):

nor-Binaltorphimine Dihydrochloride, Norbinaltorphimine, nor-BNI, κ Opioid Receptor Antagonist, nor-Binaltorphimine

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About This Item

Empirical Formula (Hill Notation):

C₄₀H₄₃N₃O₆ · 2HCl

CAS Number:

105618-26-6

Molecular Weight:

734.71

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00069374

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

Pricing and availability is not currently available.

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Properties

Product Name

nor-Binaltorphimine Dihydrochloride,

assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white to off-white

solubility

water: 50 mM

storage temp.

−20°C

SMILES string

N21CC3(C4(C(Oc%12c4c(ccc%12O)CC2C%13CC%13)c5[nH]c6c(c5C3)CC7(C98C6Oc%10c9c(ccc%10O)CC(N(C7)CC8)C%11CC%11)O)CC1)O

InChI

1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2

InChI key

GYEXSFKLGQBRBJ-UHFFFAOYSA-N

Description

General description

A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.

Biochem/physiol Actions

Primary Target
kappa opioid receptor

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kishioka, S., et al. 2013. Neurosci. Letters.In press.

Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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This Item	5.08159	5.05772	5.05880
Sigma-Aldrich 5.08017 nor-Binaltorphimine Dihydrochloride	Sigma-Aldrich 5.08159 Salvinorin A	Sigma-Aldrich 5.05772 Pirenzepine Dihydrochloride	Sigma-Aldrich 5.05880 L-745,870 Trihydrochloride
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥99% (HPLC)	assay ≥99% (HPLC)
form solid	form solid	form solid	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
storage temp. −20°C	storage temp. −70°C	storage temp. 2-8°C	storage temp. 2-8°C
storage condition OK to freeze, protect from light	storage condition OK to freeze, protect from light	storage condition OK to freeze, protect from light	storage condition OK to freeze, protect from light

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c