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S5799

Sigma-Aldrich

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt

≥95% (H-NMR), powder

Synonim(y):

BS3, Bis(sulfosuccinimidyl) suberate sodium salt

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25 MG
831,00 zł
100 MG
2770,00 zł

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25 MG
831,00 zł
100 MG
2770,00 zł

About This Item

Wzór empiryczny (zapis Hilla):
C16H18N2Na2O14S2
Numer CAS:
Masa cząsteczkowa:
572.43
Numer MDL:
Kod UNSPSC:
12352106
Identyfikator substancji w PubChem:
NACRES:
NA.22

831,00 zł


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klasa czystości

for analytical purposes

Poziom jakości

Próba

≥95% (H-NMR)

Formularz

powder

przydatność reakcji

reagent type: cross-linking reagent

rozpuszczalność

H2O: 10 mg/mL
DMF: soluble

temp. przechowywania

−20°C

ciąg SMILES

[Na+].[Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)CCCCCCC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)C1=O

InChI

1S/C16H20N2O14S2.2Na/c19-11-7-9(33(25,26)27)15(23)17(11)31-13(21)5-3-1-2-4-6-14(22)32-18-12(20)8-10(16(18)24)34(28,29)30;;/h9-10H,1-8H2,(H,25,26,27)(H,28,29,30);;/q;2*+1/p-2

Klucz InChI

MGJYOHMBGJPESL-UHFFFAOYSA-L

Opis ogólny

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt (BS3) is a water soluble, homobifunctional cross-linking reagent with amine reactivity. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates 8-atom linker.[1]

Zastosowanie

Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt (BS3) is useful for the preparation of protein-protein, receptor-ligand and hapten carrier molecule conjugates.[2][3][4]
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state.
Jang W
Molecular Cell, 31, 461-461 (2011)
Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking.
Mouradov D
Protein engineering, design & selection : PEDS, 19, 9-16 (2006)
Bovine apolipoprotein (apo)A-I displays more enhanced antioxidant and anti-atherosclerotic activity in lipid-free and lipid-bound states than human and porcine apoA-I.
Kim SM
International Journal of Molecular Medicine, 32, 843-843 (2013)
Maarten van Dinther et al.
PloS one, 8(4), e62295-e62295 (2013-05-03)
Sclerosteosis is a rare high bone mass disease that is caused by inactivating mutations in the SOST gene. Its gene product, Sclerostin, is a key negative regulator of bone formation and might therefore serve as a target for the anabolic
Huawen Lin et al.
PLoS genetics, 9(9), e1003841-e1003841 (2013-10-03)
Whole genome sequencing is a powerful tool in the discovery of single nucleotide polymorphisms (SNPs) and small insertions/deletions (indels) among mutant strains, which simplifies forward genetics approaches. However, identification of the causative mutation among a large number of non-causative SNPs

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is reconstituent procedure?

    1 answer
    1. There is no reconstitution protocol offered with this material. This product can be reconstituted in water at 10 mg/mL. Once reconstituted, solutions can be stored at 0 - 4°C for the short term. Solution stability studies have not been performed.

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