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HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Synonimy:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Metoclopramide, VETRANAL®, analytical standard,
Gatunek
human
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
SR 57227A, solid,
Gatunek
human
Metoclopramide hydrochloride, solid,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
DCEBIO, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
1-(4-Chlorophenyl)piperazine, ≥98.0% (GC),
Gatunek
rat
Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Alosetron hydrochloride, ≥98% (HPLC),
Gatunek
human
Ondansetron for LC system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Trimipramine maleate salt, ≥98% (TLC), powder,
Gatunek
human
Zimelidine dihydrochloride, solid,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Gatunek
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Gatunek
human
Fluvoxamine maleate, solid,
Gatunek
human
Sertraline hydrochloride, ≥98% (HPLC),
Gatunek
human
Citalopram hydrobromide, ≥98% (HPLC),
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Gatunek
human

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
5-Hydroxy-L-tryptophan, powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Htr3a,
Gatunek
mouse
MISSION® esiRNA, targeting human HTR3A,
Gatunek
human