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HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Synonimy:
5-HT2A, HTR2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
α-Methylserotonin maleate salt, ≥98% (HPLC),
Gatunek
human
Aripiprazole solution, 1.0 mg/mL (50:50 Methanol/Water with 1% 1N HCl), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Nortriptyline hydrochloride, ≥98% (HPLC), powder,
Gatunek
human
Mianserin hydrochloride, ,
Gatunek
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
DCEBIO, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
2,2-Diphenylethylamine, 96%,
Gatunek
rat
Haloperidol, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Haloperidol, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Haloperidol for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Haloperidol, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-HTR2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry
Anti-Serotonin receptor 2A/HTR2A Antibody, clone 9B11.1, clone 9B11.1, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
mouse, rat, sheep
Zastosowanie
Anti-HTR2A, affinity isolated antibody,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Mianserin hydrochloride, ,
Gatunek
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
Gatunek
human
Pimozide, ,
Gatunek
human, mouse, rat
Trimipramine maleate salt, ≥98% (TLC), powder,
Gatunek
human
Zimelidine dihydrochloride, solid,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Phenethylamine, purified by redistillation, ≥99.5%,
Gatunek
rat, mouse, human
Phenethylamine, ≥99%,
Gatunek
rat, mouse, human
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Trazodone hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Trazodone hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
Mifepristone, ≥98%,
Gatunek
human, mouse, rat
Haloperidol, powder,
Gatunek
human, rat
Clozapine, ,
Gatunek
human, rat

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
5-Hydroxy-L-tryptophan, powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Htr2a,
Gatunek
mouse