T9531

D-(+)-Trehalose dihydrate

≥99% (HPLC), from Saccharomyces cerevisiae

• Szinonimák: Trehalose dihydrate, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
• Tapasztalati képlet (Hill-képlet): C₁₂H₂₂O₁₁ · 2H₂O
• CAS-szám: 6138-23-4
• Molekulatömeg: 378.33
• Beilstein: 5322018
• EC-szám: 202-739-6
• MDL-szám: MFCD00071594
• UNSPSC kód: 12352201
• PubChem Substance ID: 57654693
• NACRES: NA.25

Tulajdonságok

• biológiai forrás: Saccharomyces cerevisiae
• Minőségi szint: 300
• Teszt: ≥99% (HPLC)
• form: powder
• optikai aktivitás: [α]20/D 174 to 182 °, c = 7% (w/v) in water
• technika/technikák: HPLC: suitable; PCR: suitable; cell based assay: suitable; cryopreservation: suitable
• szennyeződések: ≤5.0% EtOH; <20 ppm Trace metals
• szín: white
• mp: 97-99 °C
• oldhatóság: water: 50 mg/mL, clear, colorless
• alkalmazás(ok): advanced drug delivery; agriculture; cell analysis; life science and biopharma; sample preparation
• tárolási hőmérséklet: room temp
• SMILES string: [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
• Nemzetközi kémiai azonosító kulcs: DPVHGFAJLZWDOC-PVXXTIHASA-N

Leírás

Általános leírás

Trehalose, also known as mycose or tremalose, is a nonreducing disaccharide of glucose commonly found in fungi, bacteria, and invertebrates. Its presence in these organisms highlights its significance in various biological processes and potential applications in biochemical research and cell culture studies.

Alkalmazás

D-(+)-Trehalose dihydrate has been used:

• as a transcription factor EB (TFEB) to study its effects on an autophagy-lysosomal system in human silicosis alveolar macrophages
• as stabilizing excipient in spray-dried protein formulations
• as a cryoprotectant to study its effects on mouse testicular cell suspensions

Biokémiai/fiziológiai hatások

D-(+)-Trehalose shows anti-desiccant and cryopreservative activities. It acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. Trehalose is involved in the food, cosmetic, and pharmaceutical industries. It plays a vital role in the survival of certain insects and plants known as anhydrobionts during harsh environments such as high rates of dehydration.

Minőség

Reduced metal ion content.

Elkészítési megjegyzés

Prepared by ion exchange chromatography.

Egyéb megjegyzések

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Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)