SAB4300883

Anti-NeuN antibody produced in rabbit

affinity isolated antibody

• Szinonimák: FLJ56884, FLJ58356, FOX3, HRNBP3, RBFOX3
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: polyclonal
• application: WB
• faj reaktivitás: human, mouse, rat
• technika/technikák: western blot: 1:500-1:2000 (Cell Lysate)
• citations: 17

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• Forma: buffered aqueous solution
• molekulatömeg: 34 kDa
• faj reaktivitás: human, mouse, rat
• koncentráció: 1.0 mg/mL
• technika/technikák: western blot: 1:500-1:2000 (Cell Lysate)
• izotípus: IgG
• elérési szám: NP_001076044.1
• UniProt elérési szám: A6NFN3
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... RBFOX3(146713)

Leírás

Általános leírás

NeuN (neuronal nuclei), also known as RBFOX3 (RNA binding protein, fox-1 homolog 3), is encoded by the gene mapped to human chromosome 17q25.3. The encoded protein belongs to the RBFOX family of proteins. NeuN is present in nuclei and perinuclear cytoplasm of most of the neurons in the central nervous system (CNS) of mammals.

Egyediség

The antibody detects endogenous level of total NeuN protein.

Immunogén

Recombinant protein of human NeuN.

Alkalmazás

Anti-NeuN antibody produced in rabbit has been used in Immunohistochemical staining.

Biokémiai/fiziológiai hatások

NeuN (neuronal nuclei)/RBFOX3 (RNA binding protein, fox-1 homolog 3) is a RNA splicing factor. It controls neuronal splicing pathway. NeuN is used as a potential marker of postmitotic neurons in studies of neuronal differentiation and in the evaluation of neuronal status both in norm and pathology. Mutation in the gene is associated with risk of rolandic epilepsy. Studies have shown that in presence of neurological disorders, the protein is mislocalized.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Fizikai forma

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable