Ugrás a tartalomra
Merck

RAB0010

Sigma-Aldrich

Angiotensin II EIA Kit

for serum, plasma, culture supernatant and cell lysates

Szinonimák:

Angiotensinogen, Serpin A8

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

UNSPSC kód:
12352204
NACRES:
NA.32

faj reaktivitás

mouse, human, rat

kiszerelés

kit of 96 wells (12 strips x 8 wells)

technika/technikák

ELISA: suitable
enzyme immunoassay: suitable

bemenet

sample type cell lysate
sample type culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2.62 pg/mL
standard curve range: 0.1-1000 ng/mL

észlelési módszer

colorimetric

kiszállítva

wet ice

tárolási hőmérséklet

−20°C

Géninformáció

human ... AGT(183)

Általános leírás

The Angiotensin II Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Angiotensin II peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANGII-1 can theoretically detect all active angiotensins, including ANGI, ANGII, ANGIII and ANGIV. However, it does not detect inactive angiotensinogen.

Immunogén

Angiotensin II, synthetic peptide

Alkalmazás

Angiotensin II EIA Kit has been used for quantitative estimation of serum angiotensin-II.
For research use only. Not for use in diagnostic procedures.
Angiotensin II EIA Kit has been used for analyzing circulating and serum levels of angiotensin II (Ang II) in mice and rats respectively.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biokémiai/fiziológiai hatások

Study on in vitro model shows that mechanical stretch induced Ang II release plays a vital role in mediating stretch-induced hypertrophic response. Ang II is implicated in maintaining blood pressure and has an important role in hypertension and in the pathophysiology of cardiovascular disorders. Ang II also has an essential role in growth induction, cell migration and mitosis of vascular smooth muscle cells. It enhances the production of collagen type I and III in fibroblasts, that results in thickening of the vascular wall and myocardium, and fibrosis. Variation in Ang II gene increases the risk of myocardial infarction, hypertension and left ventricular hypertrophy. Ang II expression is associated with heart failure, cardiac remodeling, diabetes, and the proliferative and inflammatory responses to arterial injury. The pharmacological agents such as angiotensin II-converting enzyme inhibitors or angiotensin II receptor antagonists can be used for treating Ang II-induced hypertension and congestive heart failure.

Kit Components Also Available Separately

Product No.
Leírás
Biztonsági adatlap

  • RABHRP3HRP-StreptavidinBiztonsági adatlap

Piktogramok

Corrosion

Figyelmeztetés

Warning

Figyelmeztető mondatok

Óvintézkedésre vonatkozó mondatok

Veszélyességi osztályok

Met. Corr. 1

Tárolási osztály kódja

8A - Combustible corrosive hazardous materials


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