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Merck
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PHG0007

SAFC

MOPS

Gyógyszeripari előállítás

Szinonimák:

3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid

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Összes fotó(2)

About This Item

Tapasztalati képlet (Hill-képlet):
C7H15NO4S
CAS-szám:
1132-61-2
Molekulatömeg:
209.26
Beilstein:
1106776
EC-szám:
214-478-5
MDL-szám:
MFCD00006183
UNSPSC kód:
12161700
NACRES:
NA.21

biológiai forrás

synthetic

Minőségi szint

400

Teszt

≥99.5%

form

powder

technika/technikák

cell culture | mammalian: suitable

szennyeződések

Endotoxin, microbial, and trace metals; tested

pH

2.5-4 (1 M in H2O)

hasznos pH-tartomány

6.5-7.9

pKa (25 °C)

7.2

λ

1 M in H2O

alkalmasság

suitable for manufacturing use

idegen aktivitás

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

Nemzetközi kémiai azonosító kulcs

DVLFYONBTKHTER-UHFFFAOYSA-N

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Általános leírás

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Alkalmazás

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Jogi információk

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

helyettesítve

Product No.
Leírás
Árazás

137273

MOPS, EMPROVE® EVOLVE

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

230.0 °F - closed cup

Lobbanási pont (C)

110 °C - closed cup

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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MOPS sodium salt ≥99.5% (titration)

Sigma-Aldrich

M9381

MOPS sodium salt

vibrant-m

D0738000

Dextran 40 for performance test

HEPES

SAFC

RES6003H-B7

HEPES

MOPS sodium salt anhydrous, free-flowing, Redi-Dri™, ≥99.5%

Sigma-Aldrich

RDD018

MOPS sodium salt

Pepstatin A microbial, ≥75% (HPLC)

Sigma-Aldrich

P4265

Pepstatin A

Junji Suzuki et al.
Nature communications, 5, 4153-4153 (2014-06-14)
The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuring
Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability? Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
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