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Merck
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PHG0003

SAFC

MES hydrate

Gyógyszeripari előállítás

Szinonimák:

2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)

About This Item

Tapasztalati képlet (Hill-képlet):
C6H13NO4S · xH2O
CAS-szám:
1266615-59-1
Molekulatömeg:
195.24 (anhydrous basis)
MDL-szám:
MFCD00149409
UNSPSC kód:
12161700
NACRES:
NA.21

biológiai forrás

synthetic

Minőségi szint

400

form

powder

technika/technikák

cell culture | mammalian: suitable

szennyeződések

Endotoxin, microbial, and trace metals; tested

hasznos pH-tartomány

5.5-6.7

pKa 

6.1

alkalmasság

suitable for manufacturing use

idegen aktivitás

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

O.OS(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2

Nemzetközi kémiai azonosító kulcs

MIIIXQJBDGSIKL-UHFFFAOYSA-N

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Általános leírás

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Alkalmazás

MES is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Jogi információk

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

helyettesítve

Product No.
Leírás
Árazás

137271

MES hydrate, EMPROVE® EVOLVE

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Tongtong Ma et al.
International journal of pharmaceutics, 473(1-2), 296-303 (2014-07-02)
Oral delivery of antigens is patient-friendly and efficient way of treating intestinal infections. However, the efficacy of oral vaccines is limited by degradation in the gastrointestinal (GI) tract and poor absorption by enterocytes and antigen-presenting cells (APC). Here we report
Tomoya Narawa et al.
Biological & pharmaceutical bulletin, 38(4), 545-551 (2015-04-04)
The stereoselective transport of methotrexate (L-amethopterin, L-MTX) and its enantiomer (D-amethopterin, D-MTX) by the rat proton-coupled folate transporter (rPCFT) were examined using rPCFT-expressing HEK293 cells. The initial rate of uptake of [3H]-L-MTX by the rPCFT followed Michaelis-Menten kinetics, with a
M Mirazul Islam et al.
Acta biomaterialia, 12, 70-80 (2014-12-03)
The implant-host interface is a critical element in guiding tissue or organ regeneration. We previously developed hydrogels comprising interpenetrating networks of recombinant human collagen type III and 2-methacryloyloxyethyl phosphorylcholine (RHCIII-MPC) as substitutes for the corneal extracellular matrix that promote endogenous
Katelyn T Gause et al.
ACS nano, 9(3), 2433-2444 (2015-02-26)
The development of subunit antigen delivery formulations has become an important research endeavor, especially in cases where a whole cell vaccine approach has significant biosafety issues. Particle-based systems have shown particular efficacy due to their inherent immunogenicity. In some cases
Xu Yu et al.
Biosensors & bioelectronics, 66, 520-526 (2014-12-17)
A novel highly sensitive colorimetric assay for DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization was established. The DNA modified superparamagnetic beads were demonstrated to capture and enrich the target DNA in the hybridization
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