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M5284

Sigma-Aldrich

IgG1 Isotype Control from murine myeloma

clone MOPC 21, purified immunoglobulin, buffered aqueous solution

Szinonimák:

Isotype control antibody

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

UNSPSC kód:
12352203
NACRES:
NA.46

biológiai forrás

mouse

Minőségi szint

300

konjugátum

unconjugated

antitest forma

purified immunoglobulin

klón

MOPC 21, monoclonal

form

buffered aqueous solution

technika/technikák

flow cytometry: suitable

kiszállítva

wet ice

tárolási hőmérséklet

2-8°C

célzott transzláció utáni módosítás

unmodified

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Általános leírás

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.

Egyediség

IgG1 isotype control antibody is specific for anti-mouse whole serum and anti-mouse IgG1. The product does not react with antisera to mouse IgA, IgM, IgG2a, IgG2b, and IgG3.

Alkalmazás

IgG1 Isotype Control from murine myeloma has been used in:
extracellular DNA fluorescence assay
  • reactive oxygen species (ROS) production analysis
  • immunohistochemistry
  • double labelling immunohistochemistry
  • immunofluorescence
  • flow cytometry
  • immunoprecipitation

IgG1 isotype control antibodies are suitable for use in immunohistochemistry (7μg/ml) and immunoblotting. The product may also be used for flow cytometry.

Biokémiai/fiziológiai hatások

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . I
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. It mainly helps in immune defense. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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