Ugrás a tartalomra
Merck

M7894

Sigma-Aldrich

IgG1, Kappa from murine myeloma

clone MOPC 21, ascites fluid, lyophilized powder

Szinonimák:

Mouse IgG1-κ

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

MDL-szám:
UNSPSC kód:
12352203
NACRES:
NA.46

biológiai forrás

mouse

Minőségi szint

konjugátum

unconjugated

antitest forma

ascites fluid

klón

MOPC 21, monoclonal

form

lyophilized powder

alkalmazás(ok)

research pathology

tárolási hőmérséklet

2-8°C

célzott transzláció utáni módosítás

unmodified

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Általános leírás

The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.

Alkalmazás

IgG1, Kappa from murine myeloma has been used:
  • in stimulation assay and enzyme-linked immunosorbent assay (ELISA)
  • as isotype controls in islet hormone production
  • in flow cytometric analysis, in cell migration assay
  • as control antibody in evaluation of methylation

Biokémiai/fiziológiai hatások

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Feloldás

Reconstitute with 1 mL deionized water.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

The Laboratory Rat (2015)
M A Portelli et al.
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A Sharland et al.
Transplantation, 65(10), 1370-1377 (1998-06-13)
Liver transplants in the rat strain combination PVG-to-Dark Agouti are spontaneously tolerated, whereas kidney transplants in the same strain combination are rejected in 7-9 days. To identify organ-specific differences that might yield further information about the mechanism of tolerance induction
Eva Obermueller et al.
Cancer research, 64(21), 7801-7812 (2004-11-03)
Tumor growth and progression are critically controlled by alterations in the microenvironment often caused by an aberrant expression of growth factors and receptors. We demonstrated previously that tumor progression in patients and in the experimental HaCaT tumor model for skin
M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis
Schlapbach LJ, et al.
Pediatric Research, 71(4-1), 368-368 (2012)

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