M0418

Melanin

BioReagent, Synthetic, suitable for cell culture

• CAS-szám: 8049-97-6
• EC-szám: 232-473-6
• MDL-szám: MFCD00131581
• UNSPSC kód: 12352209
• NACRES: NA.75

Tulajdonságok

• biológiai forrás: synthetic
• termékcsalád: BioReagent
• Teszt: ≥97% (TLC)
• Forma: powder
• technika/technikák: cell culture | mammalian: suitable
• oldhatóság: 1 N NH₄OH: 20 mg/mL
• tárolási hőmérséklet: −20°C
• SMILES string: [nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O
• InChI: 1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
• Nemzetközi kémiai azonosító kulcs: XUMBMVFBXHLACL-UHFFFAOYSA-N

Leírás

Általános leírás

Melanin is a distinctive class of pigment found in animals, plants, bacteria, and fungi. It is an amorphous polymer formed by the polymerization of phenolic and indolic compounds.

Alkalmazás

Melanin has been used:

• to incubate normal human keratinocytes for Masson-Fontana staining
• as a standard in the determination of melanin content in normal human epidermal melanocytes and immortalized human keratinocytes
• as an absorber to mimic human skin or melanocytic nevi and melanoma

Biokémiai/fiziológiai hatások

Melanin plays a role in camouflage and energy harvesting. It also helps in protection against ionizing UV radiations, protection against biotic factors such as host defense against pathogens, and abiotic factors like heat, cold and osmotic stress. Melanin acts as a potent cation chelator and is a component of several photoprotective creams as it facilitates free radical scavenging activity. Melanin may be useful as a photo protectant in cell culture.

Elkészítési megjegyzés

Prepared by oxidation of tyrosine with hydrogen peroxide.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)