Ugrás a tartalomra
Merck

I6635

Sigma-Aldrich

Monoclonal Anti-Secretory Component (IgA) antibody produced in mouse

clone GA-1, ascites fluid

Szinonimák:

IgA Antibody, Secretory Component Antibody

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

MDL-szám:
UNSPSC kód:
12352203
NACRES:
NA.46
konjugátum:
unconjugated
application:
ELISA (i)
klón:
GA-1, monoclonal
faj reaktivitás:
human
citations:
16
technika/technikák:
indirect ELISA: 1:10,000

biológiai forrás

mouse

Minőségi szint

konjugátum

unconjugated

antitest forma

ascites fluid

antitest terméktípus

primary antibodies

klón

GA-1, monoclonal

tartalmaz

15 mM sodium azide

faj reaktivitás

human

technika/technikák

indirect ELISA: 1:10,000

izotípus

IgG1

kiszállítva

dry ice

tárolási hőmérséklet

−20°C

célzott transzláció utáni módosítás

unmodified

Általános leírás

The secretory component is a single chain glycoprotein that may occur freely or as component of the secretory immunoglobulin A (SIgA). IgA regulates the physiological balance between commensal intestinal bacteria and the defenses of the host immune system. It is the highest generated antibody isotype. IgAs are mainly secreted in the intestinal mucosa and prevent the commensal microorganisms from invading the intestines
Monoclonal Anti-Secretory Component (IgA) antibody is specific for secretory human IgA and the free secretory component. The antibody does not bind to human IgG, IgM and IgE.

Immunogén

Secretory component purified from human colostrum

Alkalmazás

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Monoclonal Anti-Secretory Component (IgA) antibody has been used in immunohistochemistry analysis and serological assays.
Monoclonal Anti-Secretory Component (IgA) antibody is suitable for use in EIA and western blot. The product may also be used for indirect ELISA (1:10,000).

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

12 - Non Combustible Liquids

WGK

nwg

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Muna Sapkota et al.
Alcoholism, clinical and experimental research, 41(12), 2093-2099 (2017-09-25)
Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a
Min Zhao et al.
Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has
B Simell et al.
The Journal of infectious diseases, 183(6), 887-896 (2001-03-10)
Local antibodies probably contribute to defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media (AOM) induce mucosal antibodies to potential vaccine candidates pneumococcal surface adhesin A (PsaA), pneumolysin (Ply), and pneumococcal surface protein A (PspA).
Influence of reactive oxygen species on secretory component in the intestinal epithelium during hyperoxia
Zhao M, et al.
Experimental and Therapeutic Medicine, 14(5), 4033-4040 (2017)
Alpha Fardah Athiyyah et al.
Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa

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