Ugrás a tartalomra
Merck

F1641

Sigma-Aldrich

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Szinonimák:

Anti-Human IgG FITC

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

MDL-szám:
UNSPSC kód:
12352203
NACRES:
NA.46

biológiai forrás

goat

Minőségi szint

konjugátum

FITC conjugate

antitest forma

affinity isolated antibody

antitest terméktípus

secondary antibodies

klón

polyclonal

form

buffered aqueous solution

technika/technikák

direct immunofluorescence: 1:32

tárolási hőmérséklet

2-8°C

célzott transzláció utáni módosítás

unmodified

Általános leírás

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ and λ myeloma proteins. The use of this product prevents background staining due to the presence of Fc receptors.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. The two heavy chains and two light chains of IgG are connected by a disulfide bond. It is a glycoprotein and mainly helps in immune defense. IgG is usually found as a monomer. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. About 70 percent of the total immunoglobulin consists of IgG. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

Immunogen

Purified human IgG

Alkalmazás

Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is suitable for use in direct immunofluorescence (1:32).
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−FITC antibody has been used in immunofluorescence studies and flow cytometric crossmatch (FCXM).

Fizikai forma

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

12 - Non Combustible Liquids

WGK

nwg

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

IgG
Encyclopedia of Immunology (1998)
Işın Sinem Bağcı et al.
Journal of biophotonics, 14(5), e202000509-e202000509 (2021-01-26)
Ex vivo confocal laser scanning microscopy (ex vivo CLSM) provides rapid, high-resolution imaging and immunofluorescence examinations of the excised tissues. We aimed to evaluate the applicability of ex vivo CLSM in histomorphological and direct immunofluorescence (DIF) examination of pemphigus vulgaris
Işın S Bağcı et al.
Journal of biophotonics, 12(9), e201800425-e201800425 (2019-04-26)
Ex vivo confocal laser scanning microscopy (ex vivo CLSM) offers an innovative diagnostic approach through vertical scanning of skin samples with a resolution close to conventional histology. In addition, it enables fluorescence detection in tissues. We aimed to assess the
Işın Sinem Bağcı et al.
Experimental dermatology, 30(5), 684-690 (2020-12-22)
Ex vivo confocal laser scanning microscopy (CLSM) offers real-time examination of excised tissue in reflectance, fluorescence and digital haematoxylin-eosin (H&E)-like staining modes enabling application of fluorescent-labelled antibodies. We aimed to assess the diagnostic performance of ex vivo CLSM in identifying
I S Bağcı et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 33(11), 2123-2130 (2019-07-03)
Ex vivo confocal laser scanning microscopy (ex vivo CLSM) is a novel diagnostic method allowing rapid, high-resolution imaging of excised skin samples. Furthermore, fluorescent detection is possible using fluorescent-labelled antibodies. To assess the applicability of ex vivo CLSM in the

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