PHR2227

Estradiol Impurity L

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: α-Estradiol, 1,3,5(10)-Estratriene-3,17α-diol, 3,17α-Dihydroxy-1,3,5(10)-estratriene, Epiestradiol
• Tapasztalati képlet (Hill-képlet): C₁₈H₂₄O₂
• CAS-szám: 57-91-0
• Molekulatömeg: 272.38
• MDL-szám: MFCD00064144
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• API-család: estradiol
• form: powder
• Analitikai műbizonylat: current certificate can be downloaded
• kiszerelés: pkg of 50 mg
• alkalmazás(ok): pharmaceutical
• tárolási hőmérséklet: 2-30°C
• SMILES string: [H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24
• InChI: 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
• Nemzetközi kémiai azonosító kulcs: VOXZDWNPVJITMN-SFFUCWETSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Alkalmazás

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biokémiai/fiziológiai hatások

Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer′s disease and ischemic stroke.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC3407 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Piktogramok: GHS08,GHS09
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H341,H351,H360F,H362,H410
• Óvintézkedésre vonatkozó mondatok: P202 - P260 - P263 - P264 - P273 - P308 + P313
• Veszélyességi osztályok: Aquatic Chronic 1 - Carc. 2 - Lact. - Muta. 2 - Repr. 1A
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable