Összes fotó(1)
Fontos dokumentumok
PHR1027
Guaifenesin
certified reference material, pharmaceutical secondary standard
Szinonimák:
Guaiacol glyceryl ether, 3-(o-Methoxyphenoxy)-1,2-propanediol, Glycerol guaiacolate, Guaifenesin
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Tapasztalati képlet (Hill-képlet):
C10H14O4
CAS-szám:
Molekulatömeg:
198.22
EC-szám:
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
NACRES:
NA.24
Javasolt termékek
grade
certified reference material
pharmaceutical secondary standard
Minőségi szint
Ügynökség
traceable to Ph. Eur. G0700000
traceable to USP 1301007
API-család
guaifenesin
Analitikai műbizonylat
current certificate can be downloaded
technika/technikák
HPLC: suitable
gas chromatography (GC): suitable
alkalmazás(ok)
pharmaceutical (small molecule)
format
neat
tárolási hőmérséklet
2-30°C
SMILES string
COc1ccccc1OCC(O)CO
InChI
1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3
Nemzetközi kémiai azonosító kulcs
HSRJKNPTNIJEKV-UHFFFAOYSA-N
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Általános leírás
Guaifenesin is an expectorant, widely used in the treatment of cough. Its mode of action involves the alleviating of cough discomfort by increasing sputum volume and decreasing its viscosity, thus resulting in effective cough.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Alkalmazás
Guaifenesin may be used as a reference standard in determining the concentration of guaifenesin present in pharmaceutical formulations and human plasma using colorimetric technique and high performance liquid chromatography (HPLC), respectively. It may also be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analízis megjegyzés
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Egyéb megjegyzések
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Lábjegyzet
To see an example of a Certificate of Analysis for this material enter LRAC3180 in the slot below. This is an example certificate only and may not be the lot that you receive.
kapcsolódó termék
Product No.
Leírás
Árazás
Figyelmeztetés
Warning
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 4 Oral
Tárolási osztály kódja
13 - Non Combustible Solids
WGK
WGK 1
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
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Az ügyfelek ezeket is megtekintették
Development and validation of a high-performance liquid chromatographic method for the determination of methocarbamol in human plasma
Naidong W, et al.
Journal of Chromatography. B, Biomedical Applications, 287-292 (1994)
Sensitive spectrophotometric method for quantitation of guaifenesin and dropropizine in their dosage forms
Abdallah.MO, et al.
International Journal of Analytical Chemistry (2010)
Development and validation of stability indicating the RP-HPLC method for the estimation of related compounds of guaifenesin in pharmaceutical dosage forms
Reddy PS, et al.
Pharmaceutical Methods, 2(4), 229-234 (2011)
Mallinath B Hadimani et al.
Journal of medicinal chemistry, 56(12), 5071-5078 (2013-06-14)
In diabetic patients, an early index of peripheral neuropathy is the slowing of conduction velocity in large myelinated neurons and a lack of understanding of the basic pathogenic mechanisms hindered therapeutics development. Racemic (R/S)-guaifenesin (1) was identified as a potent
Optimization of an improved single-column chromatographic process for the separation of enantiomers.
Monzure-Khoda Kazi et al.
Journal of chromatography. A, 1231, 22-30 (2012-03-01)
This work addresses optimization of an improved single-column chromatographic (ISCC) process for the separation of guaifenesin enantiomers. Conventional feed injection and fraction collection systems have been replaced with customized components facilitating simultaneous separation and online monitoring with the ultimate objective
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