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O0150000

Omeprazole

European Pharmacopoeia (EP) Reference Standard

Szinonimák:

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, Antra, Losec

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About This Item

Tapasztalati képlet (Hill-képlet):
C17H19N3O3S
CAS-szám:
73590-58-6
Molekulatömeg:
345.42
MDL-szám:
MFCD00083192
UNSPSC kód:
41116107
PubChem Substance ID:
329818823
NACRES:
NA.24

grade

pharmaceutical primary standard

API-család

omeprazole

gyártó/kereskedő neve

EDQM

technika/technikák

HPLC: suitable
gas chromatography (GC): suitable

alkalmazás(ok)

pharmaceutical (small molecule)

Formátum

neat

SMILES string

COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C

InChI

1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

Nemzetközi kémiai azonosító kulcs

SUBDBMMJDZJVOS-UHFFFAOYSA-N

Géninformáció

human ... ATP4A(495) , ATP4B(496)

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Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Omeprazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

kapcsolódó termék

Product No.
Leírás
Árazás

1249789

Esomeprazole magnesium, United States Pharmacopeia (USP) Reference Standard

1478505

Omeprazole, United States Pharmacopeia (USP) Reference Standard

O0151000

Omeprazole impurity D, European Pharmacopoeia (EP) Reference Standard

Y0001043

Omeprazole magnesium, European Pharmacopoeia (EP) Reference Standard

Y0001042

Omeprazole for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001028

Esomeprazole magnesium trihydrate, European Pharmacopoeia (EP) Reference Standard

Y0001660

Esomeprazole magnesium dihydrate, European Pharmacopoeia (EP) Reference Standard

1478491

Omeprazole Related Compound F and G mixture, United States Pharmacopeia (USP) Reference Standard

1478516

Omeprazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1478561

Omeprazole Related Compound I, United States Pharmacopeia (USP) Reference Standard

1478527

Omeprazole Related Compound E, United States Pharmacopeia (USP) Reference Standard

PHR1585

Esomeprazole Magnesium, Pharmaceutical Secondary Standard; Certified Reference Material

1478549

Omeprazole magnesium, United States Pharmacopeia (USP) Reference Standard

PHR1648

Omeprazole Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1649

Omeprazole Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1650

Omeprazole Related Compound I, Pharmaceutical Secondary Standard; Certified Reference Material

1478480

Omeprazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

1478479

R-Omeprazole, United States Pharmacopeia (USP) Reference Standard

BP765

Omeprazole, British Pharmacopoeia (BP) Reference Standard

PHR1988

Omeprazole Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1987

Omeprazole Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1989

Omeprazole Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1954

N′-Methyl Omeprazole, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002075

Esomeprazole sodium, European Pharmacopoeia (EP) Reference Standard

PHR9054

2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2329

Omeprazole Related Compound F and G, Pharmaceutical Secondary Standard; Certified Reference Material

Piktogramok

Exclamation markEnvironment
GHS07,GHS09

Figyelmeztetés

Warning

Figyelmeztető mondatok

H302,H317,H411

Óvintézkedésre vonatkozó mondatok

P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352

Veszélyességi osztályok

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

Sajnos jelenleg COA nem áll rendelkezésre ehhez a termékhez online.

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Omeprazole Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1478516

Omeprazole Related Compound A

Anju Nohria et al.
Journal of the American Heart Association, 3(1), e000609-e000609 (2014-01-07)
Inflammation is fundamental to the development of atherosclerosis. We examined the effect of anti-inflammatory doses of salicylate on endothelium-dependent vasodilation, a biomarker of cardiovascular risk, in a broad range of subjects. We performed a randomized, double-blind, placebo-controlled crossover trial evaluating
R P Myers et al.
The American journal of gastroenterology, 96(12), 3428-3431 (2002-01-05)
Omeprazole is a proton pump inhibitor that is used commonly in the treatment of acid-peptic disorders. Although omeprazole is generally well tolerated, serious adverse effects such as renal failure have been reported. Thus far, 17 cases of acute interstitial nephritis
Kazuhiro Shiizaki et al.
Molecular pharmacology, 85(2), 279-289 (2013-11-23)
Omeprazole (OME) induces the expression of genes encoding drug-metabolizing enzymes, such as CYP1A1, via activation of the aryl hydrocarbon receptor (AhR) both in vivo and in vitro. However, the precise mechanism of OME-mediated AhR activation is still under investigation. While
A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole.
Lars Olbe et al.
Nature reviews. Drug discovery, 2(2), 132-139 (2003-02-04)
Vaibhav Mishra et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(6), 506-511 (2013-03-07)
In continuation of our drug discovery program on Indian medicinal plants, the gastro protective mechanism of chebulinic acid isolated from Terminalia chebula fruit was investigated. Chebulinic acid was evaluated against cold restraint (CRU), aspirin (AS), alcohol (AL) and pyloric ligation
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