Összes fotó(4)
Fontos dokumentumok
G6257
Glutaraldehyde solution
Grade II, 25% in H2O
Szinonimák:
Glutaric dialdehyde solution, Pentane-1,5-dial
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(4)
About This Item
Lineáris képlet:
OHC(CH2)3CHO
CAS-szám:
Molekulatömeg:
100.12
Beilstein:
605390
MDL-szám:
UNSPSC kód:
12352114
PubChem Substance ID:
NACRES:
NA.21
Forma:
liquid
Javasolt termékek
típus
Grade II
Minőségi szint
Forma
liquid
koncentráció
25% in H2O
technika/technikák
electron microscopy: suitable
szín
colorless
hasznos pH-tartomány
2.9
mp
-10 °C ((14 °F ))
oldhatóság
water: soluble
alkalmazás(ok)
cell analysis
sample preparation
SMILES string
[H]C(CCCC([H])=O)=O
InChI
1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
Nemzetközi kémiai azonosító kulcs
SXRSQZLOMIGNAQ-UHFFFAOYSA-N
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Általános leírás
Glutaraldehyde, known as Glutaric dialdehyde or Pentane-1,5-dial, serves as a versatile reagent with applications spanning various research domains, including cell biology and biochemical research. It finds applications as a protein crosslinker, aids in enzyme immobilization for microscopy, and contributes to histochemistry and cytochemistry processes. As an amine-reactive homobifunctional crosslinker, it acts as a cell fixative before procedures like SDS-PAGE, staining, or electron microscopy, making it a valuable tool for diverse morphological studies.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Alkalmazás
Glutaraldehyde solution has been used:
- for fixation of mouse and esophageal cancer cell lines
- to crosslink amyloid-β protein
- to crosslink gelatin in 3D scaffold preparation of trachea
Biokémiai/fiziológiai hatások
Glutaraldehyde is an effective protein crosslinker and finds application in techniques like enzyme immobilisation microscopy, histochemistry and cytochemistry. It exists in different forms under acidic or neutral conditions. It is toxic to aquatic organisms. Its allergic nature leads to hypersensitivity reactions. Contact of glutaraldehyde vapors in endoscopy contributes to Colitis.
Tulajdonságok és előnyök
- Versatile and adaptable for wide variety of research applications
- Ready-made solution reduces the need for preparation time
Kiszerelés
Not refrigerated en route
Vigyázat
This grade is not recommended for use as an electron microscopy fixative.
Elkészítési megjegyzés
Not specially purified.
Egyéb megjegyzések
For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Jogi nyilatkozat
“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”
összehasonlítható termékek
Product No.
Leírás
Árazás
Figyelmeztetés
Danger
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
Célzott szervek
Respiratory system
Egyéb veszélyek
Tárolási osztály kódja
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Sorption characteristics of mixed molecules of glutaraldehyde from water on mesoporous acid-amine modified low-cost activated carbon: mechanism, isotherm, and kinetics
Lloyd M, et al.
Journal of Chemistry, 2015, 790-802 (2015)
Glutaraldehyde: behavior in aqueous solution, reaction with proteins, and application to enzyme crosslinking
Migneault I, et al.
Biotechniques, 37(5), 790-802 (2004)
Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin
Du XX, et al.
Biomedicine and Pharmacotherapy, 67(5), 417-424 (2013)
A novel tissue-engineered trachea with a mechanical behavior similar to native trachea
Park JH, et al.
Biomaterials, 62(1), 106-115 (2015)
Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls
Esparza TJ, et al.
Annals of Neurology, 73(1), 104-119 (2013)
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
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