Ugrás a tartalomra
Merck

G5882

Sigma-Aldrich

Glutaraldehyde solution

Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative

Szinonimák:

Glutaric dialdehyde solution, Pentane-1,5-dial

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
OHC(CH2)3CHO
CAS-szám:
Molekulatömeg:
100.12
Beilstein:
605390
MDL-szám:
UNSPSC kód:
12352114
PubChem Substance ID:
NACRES:
NA.21
Forma:
liquid

Minőségi szint

típus

Grade I

Forma

liquid

koncentráció

25% in H2O

technika/technikák

electron microscopy: suitable (fixative)
electron microscopy: suitable

szín

colorless

hasznos pH-tartomány

2.9

mp

-10 °C ((14 °F ))

oldhatóság

water: soluble at 20 °C

alkalmazás(ok)

cell analysis

kiszállítva

dry ice

tárolási hőmérséklet

−20°C

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

Nemzetközi kémiai azonosító kulcs

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Looking for similar products? Látogasson el ide Útmutató a termékösszehasonlításhoz

Általános leírás

Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde widely utilized as a versatile biochemical reagent. Glutaraldehyde solutions contain both monomers and polymers with the difference in their fixation properties. Its applications include serving as a protein crosslinker, facilitating enzyme immobilization in microscopy, histochemistry, and cytochemistry. This compound acts as an amine-reactive homobifunctional crosslinker and a cell fixative before SDS-PAGE, staining, or electron microscopy, making it suitable for diverse morphological studies.
Glutaraldehyde efficiently crosslinks amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it has been used in certain reactions to directly couple biotin hydrazides to nucleic acids, suggesting potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. In histology studies, Glutaraldehyde is employed to preserve tissue sections, preparing them for closer examination.

Alkalmazás

Glutaraldehyde solution has been used:
  • to fix the blood samples for scanning electron microscopy (SEM)
  • to fix scaffold pieces for SEM analysis
  • in drug treatments to treat K562 (leukemia) cells to permanently cross-link cell components

Biokémiai/fiziológiai hatások

Glutaraldehyde can be used in biomedical research to fix cells. It can also be used as a tool to investigate healthy and pathologic red blood cells. Medical equipment like spirometry tubing, endoscopes, dialyzers, hemodialysis proportioning and dialysate delivery systems, endocavitary probes, transducers, anesthesia and respiratory therapy equipment, and reuse of laparoscopic disposable plastic trocars can be disinfected with glutaraldehyde.

Tulajdonságok és előnyök

  • Versatile and adaptable for wide variety of research applications
  • Ready-made solution reduces the need for preparation time

Egyéb megjegyzések

For additional information on our range of Biochemicals, please complete this form.
Recommended for techniques demanding high purity.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Figyelmeztetés

Danger

Veszélyességi osztályok

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Célzott szervek

Respiratory system

Tárolási osztály kódja

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Egyéni védőeszköz

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

Nem találja a megfelelő verziót?

Ha egy adott verzióra van szüksége, a tétel- vagy cikkszám alapján rákereshet egy adott tanúsítványra.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Az ügyfelek ezeket is megtekintették

Malwina Sosnowska et al.
International journal of nanomedicine, 14, 6197-6215 (2019-09-10)
Degradation of the extracellular matrix (ECM) changes the physicochemical properties and dysregulates ECM-cell interactions, leading to several pathological conditions, such as invasive cancer. Carbon nanofilm, as a biocompatible and easy to functionalize material, could be used to mimic ECM structures
Jules D P Valentin et al.
Journal of colloid and interface science, 552, 247-257 (2019-05-28)
Many materials used in the medical settings such as catheters and contact lenses as well as most biological tissues are not purely elastic, but rather viscoelastic. While substrate elasticity has been investigated for its influence on bacterial adhesion, the impact
Mariafrancesca Cascione et al.
International journal of molecular sciences, 20(14) (2019-07-26)
The side effects induced by nanoparticle exposure at a cellular level are one of the priority research topics due to the steady increase in the use of nanoparticles (NPs). Recently, the focus on cellular morphology and mechanical behavior is gaining
Stéphane Jauréguiberry et al.
Blood, 124(2), 167-175 (2014-05-27)
Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
Stephanie J Bissel et al.
Journal of neuropathology and experimental neurology, 74(8), 767-777 (2015-06-27)
Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is associated with seizures and destructive periventricular white matter lesions. Despite unremarkable cerebrospinal fluid (CSF), HPeV3 RNA can

Related Content

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

Lépjen kapcsolatba a szaktanácsadással