08511

Curcumin

analytical standard

• Szinonimák: (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3
• Lineáris képlet: [HOC₆H₃(OCH₃)CH=CHCO]₂CH₂
• CAS-szám: 458-37-7
• Molekulatömeg: 368.38
• Colour Index szám: 75300
• Beilstein: 2306965
• EC-szám: 207-280-5
• MDL-szám: MFCD00008365
• UNSPSC kód: 85151701
• PubChem Substance ID: 329748594
• E szám: E100
• NACRES: NA.24

Tulajdonságok

• grade: analytical standard
• Minőségi szint: 100
• gőzsűrűség: 13 (vs air)
• Teszt: ≥98.0% (HPLC)
• Forma: powder
• eltarthatósági idő: limited shelf life, expiry date on the label
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• alkalmazás(ok): cleaning products; cosmetics; food and beverages; personal care
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
• InChI: 1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
• Nemzetközi kémiai azonosító kulcs: VFLDPWHFBUODDF-FCXRPNKRSA-N

Leírás

Általános leírás

Curcumin is an anti-inflammatory agent extracted from the roots of Curcuma longa Linn.

Alkalmazás

Curcumin may be used as a reference standard for the determination of curcumin in rat plasma by high-performance liquid chromatography method.

Biokémiai/fiziológiai hatások

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Kiszerelés

Bottomless glass bottle. Contents are inside inserted fused cone.

Egyéb megjegyzések

This compound is commonly found in plants of the genus: curcuma

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable