PHL89180

Curcumin

phyproof^® Reference Substance

• Szinonimák: (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3
• Lineáris képlet: [HOC₆H₃(OCH₃)CH=CHCO]₂CH₂
• CAS-szám: 458-37-7
• Molekulatömeg: 368.38
• Colour Index szám: 75300
• Beilstein: 2306965
• MDL-szám: MFCD00008365
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: primary reference standard
• gőzsűrűség: 13 (vs air)
• termékcsalád: phyproof^® Reference Substance
• Teszt: ≥98.0% (HPLC)
• form: powder
• gyártó/kereskedő neve: PhytoLab
• SMILES string: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
• InChI: 1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
• Nemzetközi kémiai azonosító kulcs: VFLDPWHFBUODDF-FCXRPNKRSA-N

Leírás

Általános leírás

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biokémiai/fiziológiai hatások

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Egyéb megjegyzések

This compound is commonly found in plants of the genus: curcuma

Jogi információk

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Biztonsági adatok

• Tárolási osztály kódja: 13 - Non Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable