580560

TCEP, Hydrochloride

A water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT.

• Szinonimák: TCEP, Hydrochloride, tris(2-Carboxyethyl)phosphine, HCl
• Tapasztalati képlet (Hill-képlet): C₉H₁₅O₆P · xHCl
• CAS-szám: 51805-45-9
• Molekulatömeg: 250.19 (free base basis)
• MDL-szám: MFCD00145469
• UNSPSC kód: 12352128
• NACRES: NA.25
• Forma: crystalline solid
• Teszt: ≥98% (elemental analysis)

Tulajdonságok

• Minőségi szint: 100
• Teszt: ≥98% (elemental analysis)
• Forma: crystalline solid
• reakcióalkalmasság: reagent type: reductant
• gyártó/kereskedő neve: Calbiochem^®
• tárolási körülmény: OK to freeze; desiccated
• szín: white
• oldhatóság: water: 5 mg/mL
• kiszállítva: ambient
• tárolási hőmérséklet: 2-8°C
• SMILES string: P(CCC(=O)[O-])(CCC(=O)[O-])CCC(=O)[O-]
• InChI: 1S/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)/p-3
• Nemzetközi kémiai azonosító kulcs: PZBFGYYEXUXCOF-UHFFFAOYSA-K

Leírás

Általános leírás

A water-soluble and odorless disulfide reducing agent which is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 min. TCEP is also capable of functioning as a reducing agent even in pH range of 1.5-8.5. Is more resistant to air-oxidation as compared to DTT.

Alkalmazás

• Peptide and Protein Desulfurization with Diboron Reagents.: This study investigates the use of TCEP hydrochloride in peptide and protein desulfurization, demonstrating its effectiveness in facilitating diboron-mediated reactions. (Jing & Walczak, 2024).


• A Study on Thiol-Michael Addition to Semi-Synthetic Elastin-Hyaluronan Material for Electrospun Scaffolds.: TCEP hydrochloride is utilized to enhance the thiol-Michael addition reaction in the development of electrospun scaffolds, contributing to advanced biomaterials research. (Laezza et al., 2024).


• Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis.: This paper presents an optimized protocol for RNA isolation from bovine sperm, highlighting the role of TCEP hydrochloride in improving sperm head lysis efficiency. (Tiwari et al., 2024).


• Target Recognition-Triggered Peroxidase-Mimicking Activity Depression in Homochiral Nanochannels for Identifying Cystine Enantiomers.: The study uses TCEP hydrochloride in a novel peroxidase-mimicking system to differentiate cystine enantiomers, showcasing its application in chiral analysis. (Xu et al., 2023).


• In situ digestion of alcohol-fixed cells for quantitative proteomics.: TCEP hydrochloride is applied in the in situ digestion of fixed cells to enhance the accuracy of quantitative proteomics analyses. (Hatano et al., 2023).

Kiszerelés

Packaged under inert gas

Figyelmeztetés

Toxicity: Corrosive (L)

Egyéb megjegyzések

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS05
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H314
• Óvintézkedésre vonatkozó mondatok: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Veszélyességi osztályok: Eye Dam. 1 - Skin Corr. 1B
• Tárolási osztály kódja: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1