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Merck
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D-061

Supelco

11-Deoxycortisol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C21H30O4
CAS-szám:
152-58-9
Molekulatömeg:
346.46
EC-szám:
200-659-6
MDL-szám:
MFCD00003662
UNSPSC kód:
41116107
PubChem Substance ID:
329798624
NACRES:
NA.24

grade

certified reference material

Minőségi szint

300

form

liquid

Jellemzők

Snap-N-Spike®/Snap-N-Shoot®

kiszerelés

ampule of 1 mL

gyártó/kereskedő neve

Cerilliant®

koncentráció

1.0 mg/mL in methanol

technika/technikák

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

alkalmazás(ok)

clinical testing
clinical testing

format

single component solution

tárolási hőmérséklet

−20°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

Nemzetközi kémiai azonosító kulcs

WHBHBVVOGNECLV-OBQKJFGGSA-N

Általános leírás

A new calibration material suitable for multiple LC/MS applications in clinical and diagnostic testing and endocrinology. An immediate precursor to cortisol, 11-deoxycortisol, or cortodoxone, is measured in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, pituitary tumor, and Addison′s disease.

Alkalmazás


  • Structural Analysis of Hyaluronan: The study used a mixed solvent system including 1,4-dioxane for the structural analysis of hyaluronan oligosaccharides, forming double-helical duplexes. This research is significant for pharmaceutical applications, particularly in drug delivery systems and regenerative medicine, demonstrating the solvent′s role in facilitating biochemical interactions (Kolaříková et al., 2024).

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

kapcsolódó termék

Product No.
Leírás
Árazás

A-096

Aldosterone solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

C-106

Cortisol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-113

Cortisol-D4 (9,11,12, 12-D4) solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-117

Corticosterone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-062

21-Deoxycortisol solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-076

21-Deoxycortisol-d8 (2,2,4,6,6,21,21,21-d8), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-078

11-Deoxycortisol-D5 (2,2,4,6,6-D5), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

D-085

Dexamethasone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-160

Cortisone-13C3 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-159

Corticosterone-13C3 solution, 10 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

C-216

Cortisol-13C3 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

P-123

Prednisolone-13C3 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

P-124

Prednisone-13C3 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

Figyelmeztetés

Danger

Figyelmeztető mondatok

H225,H301 + H311 + H331,H370

Óvintézkedésre vonatkozó mondatok

P210 - P260 - P280 - P301 + P310 - P311

Veszélyességi osztályok

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Tárolási osztály kódja

3 - Flammable liquids

WGK

WGK 1

Lobbanási pont (F)

49.5 °F - closed cup

Lobbanási pont (C)

9.7 °C - closed cup

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

P Magnisali et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(19), 1565-1572 (2011-04-26)
Adrenal steroid profiling, including 17α-OH progesterone (17OHP), 11-deoxycortisol (S), Δ4-androstenedione (Δ4-A) and cortisol (F) in blood spots by tandem mass spectrometry, is used for newborn screening to detect congenital adrenal hyperplasia (CAH). Pre-analytical sample processing is critical for assay specificity
Peter Thomas et al.
Environmental science & technology, 43(11), 4175-4180 (2009-07-03)
Recent studies have shown that chronic hypoxia exposure impairs reproduction in fish by interfering with endocrine function, although the mechanisms of endocrine disruption remain unclear. The effects of chronic exposure (4 or 10 weeks) to hypoxia (dissolved oxygen, DO: 1.7
Brett C McWhinney et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2863-2869 (2010-09-21)
We describe an ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC MS/MS) method suitable for a routine laboratory to determine endogenous and exogenous glucocorticoids in plasma, plasma ultrafiltrate, urine and saliva in a single analytical run. After addition of a
Michael E Baker et al.
Steroids, 76(13), 1451-1457 (2011-08-16)
The serum of Atlantic sea lamprey, a basal vertebrate, contains two corticosteroids, 11-deoxycortisol and deoxycorticosterone. Only 11-deoxycortisol has high affinity [K(d) ~ 3 nM] for the corticoid receptor [CR] in lamprey gill cytosol. To investigate the binding of 11-deoxycortisol to
Gwen E Dressing et al.
Endocrinology, 151(12), 5916-5926 (2010-10-22)
Although there is substantial evidence that membrane progestin receptors (mPRs) perform a critical physiological role in meiotic maturation of fish oocytes, it is unknown whether they are also intermediaries in progestin signaling in the surrounding follicular cells. Here, we show
View All Related Papers

Cikkek

Steroid Hormone Analysis with Supel™ Swift HLB DPX

Accurate steroid analysis in blood serum using Supel™ Swift HLB DPX Tips; UTAK and NIST standards.

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