913588

O-(2-Nitrobenzyl)-L-tyrosine hydrochloride

≥95%

• Szinonimák: (S)-2-Amino-3-(4-((2-nitrobenzyl)oxy)phenyl)propanoic acid hydrochloride, NBY, ONBY, Photo-controlled amino acid, Photocaged amino acid, Photocleavable tyrosine derivative
• Tapasztalati képlet (Hill-képlet): C₁₆H₁₇ClN₂O₅
• CAS-szám: 207727-86-4
• Molekulatömeg: 352.77
• MDL-szám: MFCD16495886
• UNSPSC kód: 12352209

Tulajdonságok

• Teszt: ≥95%
• form: powder
• elérhetőség: available only in USA
• mp: 205 °C (decomp.)
• tárolási hőmérséklet: 2-8°C
• InChI: 1S/C16H16N2O5.ClH/c17-14(16(19)20)9-11-5-7-13(8-6-11)23-10-12-3-1-2-4-15(12)18(21)22;/h1-8,14H,9-10,17H2,(H,19,20);1H/t14-;/m0./s1
• Nemzetközi kémiai azonosító kulcs: DRUCEARMIBXBOJ-UQKRIMTDSA-N

Leírás

Alkalmazás

O-(2-Nitrobenzyl)-L-tyrosine hydrochloride (NBY) is a tyrosine derivative with an o-nitrobenzyl photocage that can be cleaved with 365 nm irradiation. NBY has been genetically encoded into multiple proteins, providing an ″on switch″ for regulation. Photocaged amino acids such as these are also useful in the synthesis of photocleavable chemical tools for spatial and temporal control over released molecules in biological applications.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Egyéb megjegyzések

Site-Specific Encoding of Photoactivity in Antibodies Enables Light-Mediated Antibody-Antigen Binding on Live Cells

Time-resolved protein activation by proximal decaging in living systems

Crystal structure of a domain-swapped photoactivatable sfGFP variant provides evidence for GFP folding pathway

Light-control of the ultra-fast Gp41-1 split intein with preserved stability of a genetically encoded photo-caged amino acid in bacterial cells

Rapid and Inexpensive Evaluation of Nonstandard Amino Acid Incorporation in Escherichia coli

Biztonsági adatok

• Piktogramok: GHS02
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H242
• Óvintézkedésre vonatkozó mondatok: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Veszélyességi osztályok: Self-react. C
• Tárolási osztály kódja: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable