900917

N-Azidoacetylmannosamine-tetraacylated

95%

• Szinonimák: Ac₄ManNAz
• Tapasztalati képlet (Hill-képlet): C₁₆H₂₂N₄O₁₀
• CAS-szám: 361154-30-5
• Molekulatömeg: 430.37
• MDL-szám: MFCD26961126
• UNSPSC kód: 12352116
• NACRES: NA.22

Tulajdonságok

• Minőségi szint: 100
• Teszt: 95%
• Forma: powder or crystals
• reakcióalkalmasság: reaction type: click chemistry
• tárolási hőmérséklet: −20°C
• SMILES string: [N+](=[N-])=NCC(=O)N[C@H]1[C@H]([C@@H]([C@H](OC1OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C
• InChI: 1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13+,14-,15-,16?/m1/s1

Leírás

Alkalmazás

N-Azidoacetylmannosamine-tetraacylated (Ac₄ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable