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Sigma-Aldrich

Tetra-hidrofurano

≥99.0%, ACS reagent, contains 250 ppm BHT as inhibitor, suitable for HPLC

Sinônimo(s):

THF, Oxolano, Óxido de butileno, Óxido de tetrametileno

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About This Item

Fórmula empírica (Notação de Hill):
C4H8O
Número CAS:
109-99-9
Peso molecular:
72.11
Beilstein:
102391
Número CE:
203-726-8
Número MDL:
MFCD00005356
Código UNSPSC:
12191501
ID de substância PubChem:
329755267
NACRES:
NA.21
grau:
ACS reagent
Ensaio:
≥99.0%
técnica(s):
HPLC: suitable
p.e.:
65-67 °C (lit.)
pressão de vapor:
114 mmHg ( 15 °C)
143 mmHg ( 20 °C)
Preço e disponibilidade não estão disponíveis no momento.

Nome do produto

Tetra-hidrofurano, contains 250 ppm BHT as inhibitor, ACS reagent, ≥99.0%

grau

ACS reagent

Nível de qualidade

200

densidade de vapor

2.5 (vs air)

pressão de vapor

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Ensaio

≥99.0%

Formulário

liquid

temperatura de autoignição

610 °F

contém

250 ppm BHT as inhibitor

Lim. expl.

1.8-11.8 %

técnica(s)

HPLC: suitable

Impurezas

≤0.015% peroxide (as H2O2)
≤0.05% water

resíduo de evaporação

≤0.03%

cor

APHA: ≤20

índice de refração

n20/D 1.407 (lit.)

pH

~7

p.e.

65-67 °C (lit.)

pf

−108 °C (lit.)

solubilidade

water: soluble

densidade

0.889 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

chave InChI

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Descrição geral

O tetraidrofurano (THF) é um composto heterocíclico (éter cíclico). Ele é incolor, tem baixa viscosidade e boa solubilidade em uma ampla gama de solventes. É amplamente utilizado como solvente em síntese orgânica, sendo muito popular em reações com compostos organometálicos e reagentes de Grignard. Devido à formação de peróxidos orgânicos no armazenamento em longo prazo, o THF geralmente é estabilizado adicionando hidroxitolueno butilado (BHT). O BHT remove os radicais livres necessários para a formação de peróxido.

Aplicação

O tetraidrofurano (THF) é usado como solvente nos seguintes processos:

  • Síntese orgânica
a) Reação de Grignard
b) Compostos organometálicos
c) Reação de Reformatsky
d) Litiação
E) Redução com hidreto
f) Acoplamento catalisado por metais (Heck, Stile, Suzuki)
g) Reações mediadas por ácido de Lewis
  • Cristalização
  • Polimerização. Ex. Polimerização por RAFT (transferência reversível de cadeia por adição-fragmentação) de p-acetoxiestireno
  • Revestimentos
  • Como um ligante doador de O para formar complexos de coordenação
  • Como solvente de fase móvel em cromatografia líquida de alta eficiência

Características e benefícios

Os solventes ACS atendem ou excedem os rigorosos padrões da American Chemical Society (ACS), com especificações de teste determinadas para todos os compostos. De acordo com a American Chemical Society, o grau de reagente ACS indica que é uma substância de pureza suficiente para ser usada na maioria das análises ou reações químicas.

Outras notas

Vá para nossa alternativa mais ecológica-2-metil-tetraidrofurano - 155810

Vá para nossa alternativa mais ecológica-ciclopentil metil éter - 675989

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Órgãos-alvo

Central nervous system, Respiratory system

Perigos de suplementos

EUH019

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

-6.2 °F - closed cup

Ponto de fulgor (°C)

-21.2 °C - closed cup

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
SHBS1334
SDBB2072
SDBB0468
STBL3723
SHBR8034

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

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SAFC

1.37136

Tetra-hidrofurano

Diclorometano contains 40-150 ppm amylene as stabilizer, ACS reagent, ≥99.5%

Sigma-Aldrich

D65100

Diclorometano

Mg2Si nanoparticle synthesis for high pressure hydrogenation.
Chaudhary AL, et al.
The Journal of Physical Chemistry C, 118(2), 1240-1247 (2014)
Practical Synthesis of Di-tert-Butyl-Phosphinoferrocene.
Busacca CA, et al.
Organic Syntheses, 90, 316-326 (2013)
Synthesis of NiO/TiO2 using amphiphilic diblock copolymer brushes (PMMA-b-PAA) by reversible addition fragmentation chain-transfer poltmerization.
Hojjati B and Charpentier PA.
Polymer Reviews, 50(2), 418-418 (2009)
C N Ong et al.
British journal of industrial medicine, 48(9), 616-621 (1991-09-01)
Occupational exposure to tetrahydrofuran (THF) was studied by analysis of environmental air, blood, alveolar air, and urine from 58 workers in a video tape manufacturing plant. Head space gas chromatography (GC) with an FID detector was used for determination of
Luca Chiari et al.
The Journal of chemical physics, 138(7), 074301-074301 (2013-03-01)
We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)
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