901572

Bromo-PEG₂-acid

≥95%

• Fórmula empírica (Notação de Hill): C₇H₁₃BrO₄
• Número CAS: 1807503-92-9
• Peso molecular: 241.08
• Número MDL: MFCD28122969
• Código UNSPSC: 12352101
• NACRES: NA.22

Propriedades

• Ensaio: ≥95%
• Formulário: liquid
• adequação da reação: reagent type: linker
• grupo funcional: bromo; carboxylic acid
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: BrCCOCCOCCC(O)=O
• chave InChI: CCEBKJLCKKPYHB-UHFFFAOYSA-N

Descrição

Aplicação

Bromo-PEG₂-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG₂-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.

Informações legais

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3